Ethyl lactate

Base Information

• Chemical Name: Ethyl lactate
• CAS No.: 97-64-3
• Deprecated CAS: 2676-33-7
• Molecular Formula: C₅H₁₀O₃
• Molecular Weight: 118.133
• Hs Code.: 2918110000
• European Community (EC) Number: 202-598-0
• NSC Number: 8850
• UN Number: 1192
• UNII: F3P750VW8I
• DSSTox Substance ID: DTXSID6029127
• Nikkaji Number: J4.732E
• Wikipedia: Ethyl_lactate
• Wikidata: Q415418
• RXCUI: 1427072
• Metabolomics Workbench ID: 49151
• ChEMBL ID: CHEMBL3186323
• Mol file: 97-64-3.mol

Synonyms:ethyl lactate;ethyl lactate, (R)-isomer;ethyl lactate, (S)-isomer

Chemical Property of Ethyl lactate

Chemical Property:

• Appearance/Colour: colourless liquid
• Vapor Pressure: 1.16mmHg at 25°C
• Melting Point: -26 °C
• Refractive Index: 1.4124
• Boiling Point: 154.5 °C at 760 mmHg
• Flash Point: 54.6 °C
• PSA: 46.53000
• Density: 1.05 g/cm³
• LogP: -0.06970
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 118.062994177
• Heavy Atom Count: 8
• Complexity: 79.7
• Transport DOT Label: Flammable Liquid

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi:Irritant
• Statements: R10:; R37:; R41:
• Safety Statements: S24:; S26:; S39:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Solvents -> Esters (
• Canonical SMILES: CCOC(=O)C(C)O

Technology Process of Ethyl lactate

There total 105 articles about Ethyl lactate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-oxo-propionic acid ethyl ester (617-35-6) → ethyl 2-hydroxypropionate (97-64-3,2676-33-7)

Guidance literature:

With hydrogen; at 20 ℃; under 15001.5 Torr; Reagent/catalyst;

DOI:10.1016/j.cattod.2014.03.030

Reference yield: 97.32%

LACTIC ACID (849585-22-4,106989-11-1,26811-96-1,31587-11-8,26100-51-6) + ethanol (64-17-5) → ethyl 2-hydroxypropionate (97-64-3,2676-33-7)

Guidance literature:

With zeolite; In water; for 8h; Reflux;

Reference yield: 94.0%

(S)-(-)-ethyl 2-(tert-butyldimethylsilyloxy)propanoate (105198-38-7) → ethyl 2-hydroxypropionate (97-64-3,2676-33-7)

Guidance literature:

With potassium hydrogensulfate; In methanol; at 20 ℃; for 3h;

DOI:10.1246/cl.2004.1146

upstream raw materials:

ethyl diazoalaninate

LACTIC ACID

ethanol

sodium lactate

Downstream raw materials:

2-oxo-propionic acid ethyl ester

DL-lactic acid-(2-phenoxy-ethyl ester)

diethyl 2-cyanoglutarate

ethyl 2-ethoxypropionate

Refernces

• 1、 Chung, Iljun,Song, Byeongju,Kim, Jeongmyeong,Yun, Yongju. "Enhancing Effect of Residual Capping Agents in Heterogeneous Enantioselective Hydrogenation of α-keto Esters over Polymer-Capped Pt/Al2O3". . p. 31 - 42. Retrieved 2021/01/11.
• 2、 Shi, Junjun,Li, Fukun,Zhang, Jie,Li, Ning,Wang, Xingmin,Zhang, Xianming,Liu, Yunqi. "One-pot conversion of dihydroxyacetone into ethyl lactate by Zr-based catalysts". . p. 10935 - 10940. Retrieved 2021/03/23.