(S)-Ketorolac

Base Information

Chemical Name:(S)-Ketorolac
CAS No.:66635-92-5
Molecular Formula:C15H13 N O3
Molecular Weight:255.273
Hs Code.:
UNII:5H3TJ0A81K
DSSTox Substance ID:DTXSID901317534
Nikkaji Number:J269.531F
Wikidata:Q27145822
Mol file:66635-92-5.mol

Synonyms:(S)-Ketorolac;66635-92-5;(-)-Ketorolac;(1S)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid;Ketorolac, (S)-;UNII-5H3TJ0A81K;5H3TJ0A81K;1H-Pyrrolizine-1-carboxylicacid, 5-benzoyl-2,3-dihydro-, (1S)-;1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-, (S)-;S-(-)-Ketorolac;(S)-(-)-ketorolac;SCHEMBL14892;CHEBI:76228;HY-B0580A;DTXSID901317534;AKOS030240797;MS-23597;CS-0084964;EN300-18567395;Q27145822;(S)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid;1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-, (1S)-

Suppliers and Price of (S)-Ketorolac

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-Ketorolac
2mg
$ 155.00

ChemScene
(S)-Ketorolac 98.87%
10mg
$ 250.00

ChemScene
(S)-Ketorolac 98.87%
25mg
$ 450.00

ChemScene
(S)-Ketorolac 98.87%
5mg
$ 150.00

Cayman Chemical
(S)-Ketorolac ≥98%
1mg
$ 93.00

Cayman Chemical
(S)-Ketorolac ≥98%
5mg
$ 368.00

American Custom Chemicals Corporation
(S)-KETOROLAC 95.00%
2MG
$ 350.00

American Custom Chemicals Corporation
(S)-KETOROLAC 95.00%
50MG
$ 2194.50

American Custom Chemicals Corporation
(S)-KETOROLAC 95.00%
5MG
$ 816.75

AK Scientific
(S)-Ketorolac
5mg
$ 559.00

Total 12 raw suppliers

Chemical Property of (S)-Ketorolac

Chemical Property:

Vapor Pressure:1.52E-10mmHg at 25°C
Melting Point:160-167?C
Boiling Point:493.2°Cat760mmHg
Flash Point:252.1°C
PSA：59.30000
Density:1.33g/cm³
LogP:2.29100
Storage Temp.:Refrigerator
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:255.08954328
Heavy Atom Count:19
Complexity:376

Purity/Quality:

97% ^*data from raw suppliers

(S)-Ketorolac ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1C(=O)O
Isomeric SMILES:C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)[C@H]1C(=O)O
General Description (S)-Ketorolac is the (S)-enantiomer of ketorolac, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory properties. It is chemically described as 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid in its (S)-configuration and is also referred to as (-)-Ketorolac or S-(-)-Ketorolac. This enantiomer is synthesized through an enantioselective intramolecular coupling of pyrroles with carbonyl compounds, highlighting its significance as a therapeutically active form of the drug.

Technology Process of (S)-Ketorolac

There total 18 articles about (S)-Ketorolac which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%