(2S,3S)-2-(Dimethyl-phenyl-silanyl)-3-trimethylsilanyloxymethyl-oxirane

Base Information

• Chemical Name: (2S,3S)-2-(Dimethyl-phenyl-silanyl)-3-trimethylsilanyloxymethyl-oxirane
• CAS No.: 913193-83-6
• Molecular Formula: C₁₄H₂₄O₂Si₂
• Molecular Weight: 280.514
• Mol file: 913193-83-6.mol

Synonyms:(2S,3S)-2-(Dimethyl-phenyl-silanyl)-3-trimethylsilanyloxymethyl-oxirane

Chemical Property of (2S,3S)-2-(Dimethyl-phenyl-silanyl)-3-trimethylsilanyloxymethyl-oxirane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3S)-2-(Dimethyl-phenyl-silanyl)-3-trimethylsilanyloxymethyl-oxirane

There total 3 articles about (2S,3S)-2-(Dimethyl-phenyl-silanyl)-3-trimethylsilanyloxymethyl-oxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

chloro-trimethyl-silane (75-77-4) + [(2S,3S)-3-(dimethyl-phenyl-silanyl)-oxiran-2-yl]methanol (171868-02-3) → (2S,3S)-2-(Dimethyl-phenyl-silanyl)-3-trimethylsilanyloxymethyl-oxirane (913193-83-6)

Guidance literature:

With triethylamine;

DOI:10.1021/jo0610412

Reference yield:

Dimethylphenylsilane (766-77-8) → (2S,3S)-2-(Dimethyl-phenyl-silanyl)-3-trimethylsilanyloxymethyl-oxirane (913193-83-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 90 percent / sodium / platinum hydrosilylation catalyst / tetrahydrofuran / 24 h / Heating

2: 95 percent / diethyl L-tartrate; Ti(OiPr)4; tBuOOH

3: 90 percent / triethylamine

With titanium(IV) isopropylate; tert.-butylhydroperoxide; diethyl (2R,3R)-tartrate; sodium; triethylamine; platinum hydrosilylation catalyst; In tetrahydrofuran;

DOI:10.1021/jo0610412

Reference yield:

(E)-3-[(dimethyl)phenylsilyl]prop-2-en-1-ol (101844-21-7) → (2S,3S)-2-(Dimethyl-phenyl-silanyl)-3-trimethylsilanyloxymethyl-oxirane (913193-83-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / diethyl L-tartrate; Ti(OiPr)4; tBuOOH

2: 90 percent / triethylamine

With titanium(IV) isopropylate; tert.-butylhydroperoxide; diethyl (2R,3R)-tartrate; triethylamine;

DOI:10.1021/jo0610412

upstream raw materials:

chloro-trimethyl-silane

[(2S,3S)-3-(dimethyl-phenyl-silanyl)-oxiran-2-yl]methanol

Dimethylphenylsilane

(E)-3-[(dimethyl)phenylsilyl]prop-2-en-1-ol

Downstream raw materials:

(2S,3S)-3-(Dimethyl-phenyl-silanyl)-pent-4-ene-1,2-diol

2,4,6-Trimethyl-benzenesulfonic acid (2S,3S)-3-(dimethyl-phenyl-silanyl)-2-hydroxy-pent-4-enyl ester

(2S,3S)-2,4,6-trimethylbenzenesulfonic acid 3-(dimethylphenylsilanyl)-2-(trimethylsilanyloxy)pent-4-enyl ester