C₃₀H₃₀BrNO₅

Base Information

• Chemical Name: C₃₀H₃₀BrNO₅
• CAS No.: 1435466-82-2
• Molecular Formula: C₃₀H₃₀BrNO₅
• Molecular Weight: 564.476
• Mol file: 1435466-82-2.mol

Synonyms:C₃₀H₃₀BrNO₅

Chemical Property of C₃₀H₃₀BrNO₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₃₀H₃₀BrNO₅

There total 2 articles about C₃₀H₃₀BrNO₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1-benzyl-5-bromo-3-methylindole (1435467-13-2) + dimethyl 2-(4-methoxyphenyl)cyclopropane-1,1-dicarboxylate (75073-97-1) → C30H30BrNO5 (1435466-82-2)

Guidance literature:

With C₅₁H₆₂N₂O₂; copper(II) bis(trifluoromethanesulfonate); In toluene; at 0 ℃; for 28h; enantioselective reaction; Inert atmosphere; Schlenk technique;

DOI:10.1021/ja4042127

Reference yield:

5-bromo-3-methyl-1H-indole (10075-48-6) + benzyl bromide (100-39-0) → C30H30BrNO5 (1435466-82-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0.25 h / 0 °C / Inert atmosphere; Schlenk technique

1.2: 0.5 h / 0 - 20 °C / Schlenk technique; Inert atmosphere

2.1: C₅₁H₆₂N₂O₂; copper(II) bis(trifluoromethanesulfonate) / toluene / 28 h / 0 °C / Inert atmosphere; Schlenk technique

With C₅₁H₆₂N₂O₂; copper(II) bis(trifluoromethanesulfonate); sodium hydride; In N,N-dimethyl-formamide; toluene; mineral oil;

DOI:10.1021/ja4042127

upstream raw materials:

1-benzyl-5-bromo-3-methylindole

dimethyl 2-(4-methoxyphenyl)cyclopropane-1,1-dicarboxylate

5-bromo-3-methyl-1H-indole

benzyl bromide