Technology Process of 2-methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)morpholine
There total 6 articles about 2-methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)morpholine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate;
In
dimethyl sulfoxide;
at 70 ℃;
for 4h;
Inert atmosphere;
- Guidance literature:
-
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate;
In
dimethyl sulfoxide;
at 80 ℃;
for 4h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / dimethyl sulfoxide / 4 h / 100 °C
2.1: hydrogen; palladium on activated charcoal / 20 °C
3.1: hydrogen bromide; sodium nitrite / water / 0.5 h / -10 - 0 °C
3.2: 2 h / 60 °C
4.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / dimethyl sulfoxide / 4 h / 70 °C / Inert atmosphere
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; palladium on activated charcoal; hydrogen bromide; hydrogen; potassium acetate; potassium carbonate; sodium nitrite;
In
water; dimethyl sulfoxide;
