ethyl 1-[2-(benzyloxycarbonylamino)-1-hydroxyethyl]-cyclopropanecarboxylate

Base Information

Chemical Name:ethyl 1-[2-(benzyloxycarbonylamino)-1-hydroxyethyl]-cyclopropanecarboxylate
CAS No.:328405-08-9
Molecular Formula:C₁₆H₂₁NO₅
Molecular Weight:307.346
Hs Code.:

Synonyms:ethyl 1-[2-(benzyloxycarbonylamino)-1-hydroxyethyl]-cyclopropanecarboxylate

Suppliers and Price of ethyl 1-[2-(benzyloxycarbonylamino)-1-hydroxyethyl]-cyclopropanecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 1-[2-(benzyloxycarbonylamino)-1-hydroxyethyl]-cyclopropanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 1-[2-(benzyloxycarbonylamino)-1-hydroxyethyl]-cyclopropanecarboxylate

There total 4 articles about ethyl 1-[2-(benzyloxycarbonylamino)-1-hydroxyethyl]-cyclopropanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 220969-66-4
ethyl 1-[2-(benzyloxycarbonylamino)acetyl]-cyclopropanecarboxylate

: 328405-08-9
ethyl 1-[2-(benzyloxycarbonylamino)-1-hydroxyethyl]-cyclopropanecarboxylate

Guidance literature:: With dichloro(benzene)ruthenium(II) dimer; hydrogen; (2,2,2',2'-tetramethyl[4,4'-bibenzo[d][1,3]dioxole]-5,5'-diyl)bis(diphenylphosphine); In ethanol; at 70 ℃; for 18h; under 15001.5 Torr; optical yield given as %ee; enantioselective reaction; Autoclave;
DOI:10.1021/jo2002165

Reference yield:

: 220969-66-4
ethyl 1-[2-(benzyloxycarbonylamino)acetyl]-cyclopropanecarboxylate

: ethyl 1-[2-(benzyloxycarbonylamino)-1-hydroxyethyl]-cyclopropanecarboxylate

: 328405-08-9
ethyl 1-[2-(benzyloxycarbonylamino)-1-hydroxyethyl]-cyclopropanecarboxylate

Guidance literature:: With dichloro(benzene)ruthenium(II) dimer; hydrogen iodide; hydrogen; (2,2,2',2'-tetramethyl[4,4'-bibenzo[d][1,3]dioxole]-5,5'-diyl)bis(diphenylphosphine); In ethanol; at 70 ℃; for 18h; under 15001.5 Torr; optical yield given as %ee; enantioselective reaction; Autoclave;
DOI:10.1021/jo2002165

Reference yield:

: 1279116-77-6
ethyl 1-(2-azidoacetyl)cyclopropanecarboxylate

: 328405-08-9
ethyl 1-[2-(benzyloxycarbonylamino)-1-hydroxyethyl]-cyclopropanecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride; palladium 10% on activated carbon; hydrogen / ethanol / 2 h / 20 °C / 1551.49 Torr / Autoclave

1.2: 16.33 h / 30 °C / Cooling with ice; Inert atmosphere

2.1: dichloro(benzene)ruthenium(II) dimer; hydrogen; (2,2,2',2'-tetramethyl[4,4'-bibenzo[d][1,3]dioxole]-5,5'-diyl)bis(diphenylphosphine) / ethanol / 18 h / 70 °C / 15001.5 Torr / Autoclave

With hydrogenchloride; dichloro(benzene)ruthenium(II) dimer; palladium 10% on activated carbon; hydrogen; (2,2,2',2'-tetramethyl[4,4'-bibenzo[d][1,3]dioxole]-5,5'-diyl)bis(diphenylphosphine); In ethanol;
DOI:10.1021/jo2002165