ethyl 1-acetylcyclopropanecarboxylate

Base Information

• Chemical Name: ethyl 1-acetylcyclopropanecarboxylate
• CAS No.: 32933-03-2
• Molecular Formula: C8H12O3
• Molecular Weight: 156.181
• Hs Code.: 2902190000
• Mol file: 32933-03-2.mol

Synonyms:1-Acetylcyclopropancarbonsaeure-ethylester;1-acetyl-1-ethoxycarbonylcyclopropane;ethyl 1-acetylcyclopropanecarboxylate;ethyl 1-acetyl-1-cyclopropanecarboxylate;ethyl 1-oxoethylcyclopropane-1-carboxylate;1-Acetyl-1-cyclopropancarbonic acid ethyl ester;cyclopropane-1-acetyl-1-carboxylic acid ethyl ester;

Chemical Property of ethyl 1-acetylcyclopropanecarboxylate

Chemical Property:

• Vapor Pressure: 0.265mmHg at 25°C
• Boiling Point: 204.3°C at 760 mmHg
• Flash Point: 79.5°C
• PSA: 43.37000
• Density: 1.139g/cm³
• LogP: 0.91870
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

Ethyl1-acetylcyclopropanecarboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 1-acetylcyclopropanecarboxylate

There total 17 articles about ethyl 1-acetylcyclopropanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

ethyl acetoacetate (141-97-9) + ethylene dibromide (106-93-4) → ethyl 1-acetylcyclopropanecarboxylate (32933-03-2)

Guidance literature:

With potassium carbonate; [bmim]Br; In N,N-dimethyl-formamide; at 20 ℃; for 6h;

DOI:10.1016/j.tetlet.2004.11.141

Reference yield: 80.0%

ethyl acetoacetate (141-97-9) + ethylene dibromide (106-93-4) → ethyl 2-methyl-4,5-dihydrofuran-3-carboxylate (2986-03-0) + ethyl 1-acetylcyclopropanecarboxylate (32933-03-2)

Guidance literature:

With potassium carbonate; In dimethyl sulfoxide; at 20 ℃; for 8h;

Reference yield: 75.0%

ethyl acetoacetate (141-97-9) + 1,2-dichloro-ethane (107-06-2,52399-93-6) → ethyl 1-acetylcyclopropanecarboxylate (32933-03-2)

Guidance literature:

With tetrabutylammomium bromide; cyclohexene; electrolysis (platinum cathode, carbon anode);

DOI:10.1007/BF00959604

upstream raw materials:

2-(2-bromo-ethyl)-acetoacetic acid ethyl ester

sodium ethanolate

ethyl acetoacetate

ethylene dibromide

Downstream raw materials:

1-acetylcyclopropane-1-carboxamide

7-methyl-5,6-diazaspiro[2.4]hept-6-en-4-one

3-Ethoxy-5-methyl-4-(2-chloroethyl)pyrazole Hydrochloride

5-benzyl-5-azaspiro[2.4]heptane-4,7-dione