2,2'-bis[N-(1S)-(1-isobutyl-2-hydroxyethyl)carbamoyl]diphenylamine

Base Information

• Chemical Name: 2,2'-bis[N-(1S)-(1-isobutyl-2-hydroxyethyl)carbamoyl]diphenylamine
• CAS No.: 815575-16-7
• Molecular Formula: C₂₆H₃₇N₃O₄
• Molecular Weight: 455.597
• Mol file: 815575-16-7.mol

Synonyms:2,2'-bis[N-(1S)-(1-isobutyl-2-hydroxyethyl)carbamoyl]diphenylamine

Chemical Property of 2,2'-bis[N-(1S)-(1-isobutyl-2-hydroxyethyl)carbamoyl]diphenylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2'-bis[N-(1S)-(1-isobutyl-2-hydroxyethyl)carbamoyl]diphenylamine

There total 1 articles about 2,2'-bis[N-(1S)-(1-isobutyl-2-hydroxyethyl)carbamoyl]diphenylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

(S)-2-amino-4-methylpentan-1-ol (7533-40-6,14438-11-0) + Vanadox (579-92-0) → 2,2'-bis[N-(1S)-(1-isobutyl-2-hydroxyethyl)carbamoyl]diphenylamine (815575-16-7)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1016/j.tetasy.2004.09.011

Reference yield: 47.0%

2,2'-bis[N-(1S)-(1-isobutyl-2-hydroxyethyl)carbamoyl]diphenylamine (815575-16-7) → bis[2-((4S)-4-isobutyl-4,5-dihydrothiazol-2-yl)phenyl]amine

Guidance literature:

With pyridine; tetraphosphorus decasulfide; for 22h; Heating;

DOI:10.1016/j.tetasy.2004.09.011

Reference yield:

methanesulfonyl chloride (124-63-0) + 2,2'-bis[N-(1S)-(1-isobutyl-2-hydroxyethyl)carbamoyl]diphenylamine (815575-16-7) → Methanesulfonic acid (S)-2-{2-[2-((S)-1-methanesulfonyloxymethyl-3-methyl-butylcarbamoyl)-phenylamino]-benzoylamino}-4-methyl-pentyl ester

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 20h;

DOI:10.1016/j.tetasy.2004.09.011

upstream raw materials:

(S)-2-amino-4-methylpentan-1-ol

Vanadox