4,6-O-benzylidene-2-O-(tert-butyldimethylsilyl)-3-deoxy-3-C-(2-pivaloyloxyethyl)-α-D-altropyranoside

Base Information

Chemical Name:4,6-O-benzylidene-2-O-(tert-butyldimethylsilyl)-3-deoxy-3-C-(2-pivaloyloxyethyl)-α-D-altropyranoside
CAS No.:1439381-79-9
Molecular Formula:C₂₇H₄₄O₇Si
Molecular Weight:508.728
Hs Code.:

Synonyms:4,6-O-benzylidene-2-O-(tert-butyldimethylsilyl)-3-deoxy-3-C-(2-pivaloyloxyethyl)-α-D-altropyranoside

Suppliers and Price of 4,6-O-benzylidene-2-O-(tert-butyldimethylsilyl)-3-deoxy-3-C-(2-pivaloyloxyethyl)-α-D-altropyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4,6-O-benzylidene-2-O-(tert-butyldimethylsilyl)-3-deoxy-3-C-(2-pivaloyloxyethyl)-α-D-altropyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4,6-O-benzylidene-2-O-(tert-butyldimethylsilyl)-3-deoxy-3-C-(2-pivaloyloxyethyl)-α-D-altropyranoside

There total 5 articles about 4,6-O-benzylidene-2-O-(tert-butyldimethylsilyl)-3-deoxy-3-C-(2-pivaloyloxyethyl)-α-D-altropyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: methyl 4,6-O-benzylidene-2-O-(tert-butyldimethylsilyl)-3-deoxy-3-C-(2-hydroxyethyl)-α-D-altropyranoside

: 3282-30-2
pivaloyl chloride

: 1439381-79-9
4,6-O-benzylidene-2-O-(tert-butyldimethylsilyl)-3-deoxy-3-C-(2-pivaloyloxyethyl)-α-D-altropyranoside

Guidance literature:: With pyridine; In dichloromethane; at 0 - 20 ℃; for 1h; Inert atmosphere;
DOI:10.1021/ml400098w

Reference yield:

: methyl 4,6-O-benzylidene-3-deoxy-3-C-ethenyl-α-D-altropyranoside

: 1439381-79-9
4,6-O-benzylidene-2-O-(tert-butyldimethylsilyl)-3-deoxy-3-C-(2-pivaloyloxyethyl)-α-D-altropyranoside

Guidance literature:: Multi-step reaction with 4 steps

1: 2,6-dimethylpyridine / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

2: tetrahydrofuran / 1.5 h / 0 - 20 °C / Inert atmosphere

3: sodium hydroxide; dihydrogen peroxide / 16 h / 20 °C / Inert atmosphere

4: pyridine / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere

With pyridine; 2,6-dimethylpyridine; dihydrogen peroxide; sodium hydroxide; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ml400098w

Reference yield:

: 1439381-77-7
4,6-O-benzylidene-3-deoxy-2-O-(tert-butyldimethylsilyl)-3-C-ethenyl-α-D-altropyranoside

: 1439381-79-9
4,6-O-benzylidene-2-O-(tert-butyldimethylsilyl)-3-deoxy-3-C-(2-pivaloyloxyethyl)-α-D-altropyranoside

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran / 1.5 h / 0 - 20 °C / Inert atmosphere

2: sodium hydroxide; dihydrogen peroxide / 16 h / 20 °C / Inert atmosphere

3: pyridine / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere

With pyridine; dihydrogen peroxide; sodium hydroxide; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ml400098w