N-((4-methylphenyl)methyl)-N-(1-(2-methylpropyl)piperidin-4-yl)-N’-phenylmethylcarbamide

Base Information

Chemical Name:N-((4-methylphenyl)methyl)-N-(1-(2-methylpropyl)piperidin-4-yl)-N’-phenylmethylcarbamide
CAS No.:359877-54-6
Molecular Formula:C₂₅H₃₅N₃O
Molecular Weight:393.572
Hs Code.:

Synonyms:N-((4-methylphenyl)methyl)-N-(1-(2-methylpropyl)piperidin-4-yl)-N’-phenylmethylcarbamide

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Chemical Property of N-((4-methylphenyl)methyl)-N-(1-(2-methylpropyl)piperidin-4-yl)-N’-phenylmethylcarbamide

Chemical Property:

Purity/Quality:

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Technology Process of N-((4-methylphenyl)methyl)-N-(1-(2-methylpropyl)piperidin-4-yl)-N’-phenylmethylcarbamide

There total 5 articles about N-((4-methylphenyl)methyl)-N-(1-(2-methylpropyl)piperidin-4-yl)-N’-phenylmethylcarbamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 359877-51-3
N-((4-methylphenyl)methyl)-N-(piperidin-4-yl)-N’-phenylmethylcarbamide

: 78-84-2
isobutyraldehyde

: 359877-54-6
N-((4-methylphenyl)methyl)-N-(1-(2-methylpropyl)piperidin-4-yl)-N’-phenylmethylcarbamide

Guidance literature:: N-((4-methylphenyl)methyl)-N-(piperidin-4-yl)-N’-phenylmethylcarbamide; isobutyraldehyde; In ethanol; at 20 ℃; for 48h;

With acetic anhydride; In ethanol; for 24h;

Reference yield:

: 359877-52-4
tert-butyl 4-((4-methylphenyl)methyl)aminopiperidine carboxylate

: 359877-54-6
N-((4-methylphenyl)methyl)-N-(1-(2-methylpropyl)piperidin-4-yl)-N’-phenylmethylcarbamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: methanol; dichloromethane / 48 h / 20 °C

1.2: 24 h

2.1: hydrogenchloride / 1,4-dioxane; diethyl ether / 1 h / 20 °C

3.1: solid-supported borohydride / ethanol / 48 h / 20 °C

3.2: 24 h

With hydrogenchloride; In 1,4-dioxane; methanol; diethyl ether; ethanol; dichloromethane;

Reference yield:

: 359877-53-5
N-((4-methylphenyl)methyl)-N-(1-(tert-butyloxycarbonyl)piperidin-4-yl)-N'-phenylmethylcarbamide

: 359877-54-6
N-((4-methylphenyl)methyl)-N-(1-(2-methylpropyl)piperidin-4-yl)-N’-phenylmethylcarbamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride / 1,4-dioxane; diethyl ether / 1 h / 20 °C

2.1: solid-supported borohydride / ethanol / 48 h / 20 °C

2.2: 24 h

With hydrogenchloride; In 1,4-dioxane; diethyl ether; ethanol;