Technology Process of 3-PHENYL-6-IODOPYRIDAZINE
There total 5 articles about 3-PHENYL-6-IODOPYRIDAZINE which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); potassium carbonate;
In
1,4-dioxane; methanol;
at 95 ℃;
for 12h;
Inert atmosphere;
DOI:10.1016/j.tetlet.2018.04.015
- Guidance literature:
-
3-phenylpyridazine;
With
2,2,6,6-tetramethylpiperidinyl-lithium;
In
tetrahydrofuran;
at -78 ℃;
for 0.0833333h;
Inert atmosphere;
With
iodine;
In
tetrahydrofuran;
at -78 - 20 ℃;
regioselective reaction;
Inert atmosphere;
DOI:10.1002/anie.201903839
- Guidance literature:
-
C11H8F3N2;
With
zinc chloride-2,2,6,6-tetramethylpiperidin-1-ide lithium chloride complex;
In
tetrahydrofuran;
at -78 ℃;
for 0.333333h;
Inert atmosphere;
With
iodine;
In
tetrahydrofuran;
regioselective reaction;
Inert atmosphere;
DOI:10.1002/anie.201903839
