7-Hydroxy-2,5-dimethyl-3-(2,4-dimethoxyphenyl)-pyrazolo[1,5-a] pyrimidine

Base Information

Chemical Name:7-Hydroxy-2,5-dimethyl-3-(2,4-dimethoxyphenyl)-pyrazolo[1,5-a] pyrimidine
CAS No.:863550-43-0
Molecular Formula:C₁₆H₁₇N₃O₃
Molecular Weight:299.329
Hs Code.:
DSSTox Substance ID:DTXSID801168112

Synonyms:SCHEMBL5729669;TWFOINJTQMKAMC-UHFFFAOYSA-N;DTXSID801168112;7-hydroxy-2,5-dimethyl-3-(2,4-dimethoxyphenyl)-pyrazolo[1,5-a] pyrimidine;863550-43-0;3-(2,4-Dimethoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-ol

Suppliers and Price of 7-Hydroxy-2,5-dimethyl-3-(2,4-dimethoxyphenyl)-pyrazolo[1,5-a] pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7-Hydroxy-2,5-dimethyl-3-(2,4-dimethoxyphenyl)-pyrazolo[1,5-a] pyrimidine

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:299.12699141
Heavy Atom Count:22
Complexity:579

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=O)N2C(=N1)C(=C(N2)C)C3=C(C=C(C=C3)OC)OC

Technology Process of 7-Hydroxy-2,5-dimethyl-3-(2,4-dimethoxyphenyl)-pyrazolo[1,5-a] pyrimidine

There total 4 articles about 7-Hydroxy-2,5-dimethyl-3-(2,4-dimethoxyphenyl)-pyrazolo[1,5-a] pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 141-97-9
ethyl acetoacetate

: 863550-42-9
4-(2,4-dimethoxy-phenyl)-5-methyl-2H-pyrazol-3-ylamine

: 863550-43-0
7-Hydroxy-2,5-dimethyl-3-(2,4-dimethoxyphenyl)-pyrazolo[1,5-a]pyrimidine

Guidance literature:: In 1,4-dioxane; Heating;
DOI:10.1016/j.bmcl.2004.05.019

Reference yield:

: 1891-11-8
(2,4-dimethoxyphenyl)acetonitrile

: 863550-43-0
7-Hydroxy-2,5-dimethyl-3-(2,4-dimethoxyphenyl)-pyrazolo[1,5-a]pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaH / tetrahydrofuran

1.2: tetrahydrofuran

2.1: NH₂NH₂*HCl / aq. ethanol / Heating

3.1: dioxane / Heating

With hydrazine hydrochloride; sodium hydride; In tetrahydrofuran; 1,4-dioxane; ethanol;
DOI:10.1016/j.bmcl.2004.05.019

Reference yield:

: 332179-40-5
2-(2,4-dimethoxyphenyl)-3-oxobutanenitrile

: 863550-43-0
7-Hydroxy-2,5-dimethyl-3-(2,4-dimethoxyphenyl)-pyrazolo[1,5-a]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: NH₂NH₂*HCl / aq. ethanol / Heating

2: dioxane / Heating

With hydrazine hydrochloride; In 1,4-dioxane; ethanol;
DOI:10.1016/j.bmcl.2004.05.019