methyl 4-(5,5-difluoro-1,3,7,9-tetramethyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)benzoate

Base Information

• Chemical Name: methyl 4-(5,5-difluoro-1,3,7,9-tetramethyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)benzoate
• CAS No.: 937717-24-3
• Molecular Formula: C₂₁H₂₁BF₂N₂O₂
• Molecular Weight: 382.218
• Mol file: 937717-24-3.mol

Synonyms:methyl 4-(5,5-difluoro-1,3,7,9-tetramethyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)benzoate

Chemical Property of methyl 4-(5,5-difluoro-1,3,7,9-tetramethyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 4-(5,5-difluoro-1,3,7,9-tetramethyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)benzoate

There total 12 articles about methyl 4-(5,5-difluoro-1,3,7,9-tetramethyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(Z)-methyl 4-((3,5-dimethyl-1H-pyrrol-2-yl) (3,5-dimethyl-2H-pyrrol-2-ylidene)methyl)benzoate + boron trifluoride diethyl etherate (109-63-7) → methyl 4-(5,5-difluoro-1,3,7,9-tetramethyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)benzoate (937717-24-3)

Guidance literature:

(Z)-methyl 4-((3,5-dimethyl-1H-pyrrol-2-yl) (3,5-dimethyl-2H-pyrrol-2-ylidene)methyl)benzoate; With triethylamine; In toluene; at 20 ℃; for 0.25h;

boron trifluoride diethyl etherate; In toluene; at 80 ℃; for 0.75h; Inert atmosphere;

DOI:10.1016/j.carres.2019.107840

Reference yield: 96.2%

C21H22N2O2 (1202222-31-8) → methyl 4-(5,5-difluoro-1,3,7,9-tetramethyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)benzoate (937717-24-3)

Guidance literature:

With boron trifluoride diethyl etherate; triethylamine; In toluene; at 20 ℃; for 3h;

DOI:10.1271/bbb.80899

Reference yield: 56.0%

2,4-dimethyl-1H-pyrrole (625-82-1) + boron trifluoride diethyl etherate (109-63-7) + methyl 4-formylbenzoate (1571-08-0) → methyl 4-(5,5-difluoro-1,3,7,9-tetramethyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)benzoate (937717-24-3)

Guidance literature:

2,4-dimethyl-1H-pyrrole; methyl 4-formylbenzoate; With trifluoroacetic acid; In dichloromethane; for 4h; Inert atmosphere;

With chloranil; at 0 ℃; for 0.5h;

boron trifluoride diethyl etherate; With triethylamine; at 0 ℃;

DOI:10.1016/j.dyepig.2019.01.061

upstream raw materials:

C₂₁H₂₂N₂O₂

C₂₁H₂₄N₂O₂

boron trifluoride diethyl etherate

2,4-dimethyl-1H-pyrrole