(E)-2-(2-Benzylidenehydrazinyl)benzoic acid

Base Information

• Chemical Name: (E)-2-(2-Benzylidenehydrazinyl)benzoic acid
• CAS No.: 4036-59-3
• Molecular Formula: C14H12N2O2
• Molecular Weight: 240.261
• Hs Code.: 2928000090
• NSC Number: 9359
• Mol file: 4036-59-3.mol

Synonyms:(E)-2-(2-BENZYLIDENEHYDRAZINYL)BENZOIC ACID;686267-65-2;2-[(2E)-2-benzylidenehydrazinyl]benzoic acid;4036-59-3;(E)-2-(2-Benzylidenehydrazinyl)benzoicacid;MLS002638085;NSC9359;2-[(2E)-2-Benzylidenehydrazino]benzoic acid;SCHEMBL1522386;NSC-9359;MFCD02246103;STL134671;AKOS005744939;o-(2-Benzylidenehydrazino)benzoic acid;AS-45510;CS-0171237;2-[(2E)-2-Benzylidenehydrazino]benzoic acid #;A915732

Chemical Property of (E)-2-(2-Benzylidenehydrazinyl)benzoic acid

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 425.3°Cat760mmHg
• Flash Point: 211°C
• PSA: 61.69000
• Density: 1.17g/cm³
• LogP: 2.90380
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 240.089877630
• Heavy Atom Count: 18
• Complexity: 298

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=NNC2=CC=CC=C2C(=O)O
• Isomeric SMILES: C1=CC=C(C=C1)/C=N/NC2=CC=CC=C2C(=O)O

Technology Process of (E)-2-(2-Benzylidenehydrazinyl)benzoic acid

There total 16 articles about (E)-2-(2-Benzylidenehydrazinyl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-hydrazinobenzoic acid hydrochloride (33906-30-8,52356-01-1) + benzaldehyde (100-52-7) → 2-[(2E)-2-benzylidenehydrazino]benzoic acid (4036-59-3)

Guidance literature:

In ethanol;

DOI:10.1016/j.bmcl.2005.01.071

Reference yield: 90.0%

C32H25N2O2P (83412-86-6) → 2-benzylidene-1-(2-carboxyphenyl)hydrazine (4036-59-3)

Guidance literature:

With sodium hydroxide; In ethanol; for 1h; Ambient temperature;

Reference yield:

3-benzylideneamino-1,2,3-benzotriazin-4-one (56070-95-2) + furan-2,3,5(4H)-trione pyridine (1:1) → 2-benzylidene-1-(2-carboxyphenyl)hydrazine (4036-59-3) + benzaldehyde (100-52-7)

Guidance literature:

upstream raw materials:

3-benzylideneamino-1,2,3-benzotriazin-4-one

ethanol

N-benzyl-2-nitrosobenzamide

C₃₂H₂₅N₂O₂P

Downstream raw materials:

2-benzylidene-1-(2-methoxycarbonylphenyl)hydrazine

1-(cyclohexylideneamino)-3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxyguinolin-2(1H)-one

1-{[(2-bromophenyl)methylene]amino}-3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxyquinolin-2(1H)-one

1-{[(3-bromophenyl)methylene]amino}-3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxyquinolin-2(1H)-one

Refernces

• 1、 Kool, Eric T.,Park, Do-Hyoung,Crisalli, Pete. "Fast hydrazone reactants: Electronic and acid/base effects strongly influence rate at biological pH". supporting information. p. 17663 - 17666. Retrieved 2014/01/06.
• 2、 Tezcan, Habibe. "Synthesis and spectral properties of some bis-substituted formazans". . p. 971 - 979. Retrieved 2008/09/20.