Cyclohexanol, 4-aMino-, cis-, 2,2,2-trifluoroacetate

Base Information

• Chemical Name: Cyclohexanol, 4-aMino-, cis-, 2,2,2-trifluoroacetate
• CAS No.: 809288-10-6
• Molecular Formula: C₂HF₃O₂*C₆H₁₃NO
• Molecular Weight: 229.199
• Mol file: 809288-10-6.mol

Synonyms:cis-4-aminocyclohexanol trifluoroacetic acid salt

Chemical Property of Cyclohexanol, 4-aMino-, cis-, 2,2,2-trifluoroacetate

Chemical Property:

Purity/Quality:

cis-4-Aminocyclohexyl2,2,2-trifluoroacetate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclohexanol, 4-aMino-, cis-, 2,2,2-trifluoroacetate

There total 1 articles about Cyclohexanol, 4-aMino-, cis-, 2,2,2-trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3-aza-2-oxabicyclo[2.2.2]oct-5-ene trifluoroacetic acid salt (809288-09-3) → cis-4-aminocyclohexanol trifluoroacetic acid salt (809288-10-6)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In ethanol; at 20 ℃; for 6.5h; under 2550.26 - 3075.31 Torr;

Reference yield:

cis-4-aminocyclohexanol trifluoroacetic acid salt (809288-10-6) + 2,4-difluoro-benzoic acid (1583-58-0) → 2-(cis-4-aminocyclohexyl-oxy)-4-fluorobenzoic acid

Guidance literature:

With sodium hydride; In dimethyl sulfoxide; at 15 ℃; for 22.5h;

upstream raw materials:

3-aza-2-oxabicyclo[2.2.2]oct-5-ene trifluoroacetic acid salt

Refernces