Ridazin

Base Information

Chemical Name:Ridazin
CAS No.:5060-56-0
Molecular Formula:C20H23ClN2S
Molecular Weight:358.93
Hs Code.:2934300000
NSC Number:186055
DSSTox Substance ID:DTXSID001032387
Nikkaji Number:J13.727H
ChEMBL ID:CHEMBL3133836
Mol file:5060-56-0.mol

Synonyms:NP 207;piperidylchlorophenothiazine

Suppliers and Price of Ridazin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
PIPERIDYLCHLOROPHENOTHIAZINE 95.00%
5MG
$ 498.16

Total 6 raw suppliers

Chemical Property of Ridazin

Chemical Property:

Vapor Pressure:7.63E-10mmHg at 25°C
Boiling Point:492.5°C at 760 mmHg
Flash Point:251.7°C
PSA：31.78000
Density:1.197g/cm³
LogP:5.82000
XLogP3:6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:358.1270476
Heavy Atom Count:24
Complexity:420

Purity/Quality:

99% ^*data from raw suppliers

PIPERIDYLCHLOROPHENOTHIAZINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl

Technology Process of Ridazin

There total 8 articles about Ridazin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 102176-92-1
2-chloro-10-(2-(piperidin-2-yl)ethyl)-10H-phenothiazine

: 5060-56-0
2-chloro-10-(2-(1-methylpiperidin-2-yl)ethyl)-10H-phenothiazine

Guidance literature:: formaldehyd; 2-chloro-10-(2-(piperidin-2-yl)ethyl)-10H-phenothiazine; In tetrahydrofuran; water; at 20 ℃; for 0.5h; Inert atmosphere;

With sodium tris(acetoxy)borohydride; In tetrahydrofuran; water; at 20 ℃; for 24h; Inert atmosphere;
DOI:10.1016/j.ejmech.2016.12.042

Reference yield:

: 210564-52-6
t-butyl 2-(2-bromoethyl)piperidine-1-carboxylate

: 5060-56-0
2-chloro-10-(2-(1-methylpiperidin-2-yl)ethyl)-10H-phenothiazine

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.33 h / 0 - 20 °C / Inert atmosphere

1.2: 12 h / 20 °C / Inert atmosphere

2.1: hydrogenchloride / ethyl acetate / 24 h / 20 °C / Inert atmosphere

3.1: tetrahydrofuran; water / 0.5 h / 20 °C / Inert atmosphere

3.2: 24 h / 20 °C / Inert atmosphere

With hydrogenchloride; sodium hydride; In tetrahydrofuran; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2016.12.042

Reference yield:

: t-butyl 2-(2-(2-chloro-10H-phenothiazin-10-yl)ethyl)piperidine-1-carboxylate

: 5060-56-0
2-chloro-10-(2-(1-methylpiperidin-2-yl)ethyl)-10H-phenothiazine

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride / ethyl acetate / 24 h / 20 °C / Inert atmosphere

2.1: tetrahydrofuran; water / 0.5 h / 20 °C / Inert atmosphere

2.2: 24 h / 20 °C / Inert atmosphere

With hydrogenchloride; In tetrahydrofuran; water; ethyl acetate;
DOI:10.1016/j.ejmech.2016.12.042