1-hydroxy-2-adamantanone

Base Information

• Chemical Name: 1-hydroxy-2-adamantanone
• CAS No.: 26921-51-7
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.22
• Mol file: 26921-51-7.mol

Synonyms:1-hydroxy-2-adamantanone

Chemical Property of 1-hydroxy-2-adamantanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-hydroxy-2-adamantanone

There total 1 articles about 1-hydroxy-2-adamantanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

adamantane (281-23-2) → 2-Adamantanone (700-58-3) + 1-adamanthanol (768-95-6) + 4-protoadamantanone (27567-85-7) + 1-hydroxy-2-adamantanone (26921-51-7)

Guidance literature:

With C₉₆H₉₆Fe₂N₁₆O; tetrabutylammonium oxone; In dichloromethane; at 20 ℃; for 0.166667h;

DOI:10.1016/j.tetlet.2010.10.023

Reference yield: 70.0%

1-hydroxy-2-adamantanone (26921-51-7) + trifluoroacetic anhydride (407-25-0) → C10H14O3 (1000622-44-5) + C10H14O4 (1342302-69-5) + C10H16O5 (1342302-71-9)

Guidance literature:

With dihydrogen peroxide; regioselective reaction;

DOI:10.1016/j.mencom.2011.09.003

Reference yield:

1-hydroxy-2-adamantanone (26921-51-7) → 2-Methylenadamant-1-yl-p-toluolsulfonat (26215-87-2)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) DMSO, NaH, (ii) /BRN= 2046479/

2: (i) nBuLi, (ii) /BRN= 607898/

DOI:10.1021/ja00709a040

upstream raw materials:

adamantane

Downstream raw materials:

2-Methylenadamant-1-yl-p-toluolsulfonat

C₁₀H₁₄O₃

C₁₀H₁₄O₄

C₁₀H₁₆O₅