(E)-2-(4-chlorophenyl)-2,3-dihydro-3-[2-(trimethylammonium)ethylidene]-1H-pyrrolo[3,4-b]quinolin-1-one iodide

Base Information

• Chemical Name: (E)-2-(4-chlorophenyl)-2,3-dihydro-3-[2-(trimethylammonium)ethylidene]-1H-pyrrolo[3,4-b]quinolin-1-one iodide
• CAS No.: 1028684-24-3
• Molecular Formula: C₂₂H₂₁ClN₃O*I
• Molecular Weight: 505.786
• Mol file: 1028684-24-3.mol

Synonyms:(E)-2-(4-chlorophenyl)-2,3-dihydro-3-[2-(trimethylammonium)ethylidene]-1H-pyrrolo[3,4-b]quinolin-1-one iodide

Chemical Property of (E)-2-(4-chlorophenyl)-2,3-dihydro-3-[2-(trimethylammonium)ethylidene]-1H-pyrrolo[3,4-b]quinolin-1-one iodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-2-(4-chlorophenyl)-2,3-dihydro-3-[2-(trimethylammonium)ethylidene]-1H-pyrrolo[3,4-b]quinolin-1-one iodide

There total 1 articles about (E)-2-(4-chlorophenyl)-2,3-dihydro-3-[2-(trimethylammonium)ethylidene]-1H-pyrrolo[3,4-b]quinolin-1-one iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

(E)-2-(4-chlorophenyl)-2,3-dihydro-3-[2-(dimethylamino)ethylidene]-1H-pyrrolo[3,4-b]quinolin-1-one (1028684-23-2) + methyl iodide (74-88-4) → (E)-2-(4-chlorophenyl)-2,3-dihydro-3-[2-(trimethylammonium)ethylidene]-1H-pyrrolo[3,4-b]quinolin-1-one iodide (1028684-24-3)

Guidance literature:

In diethyl ether; ethanol; at 20 ℃; for 48h;

DOI:10.1016/j.bmc.2007.06.044

Reference yield: 73.0%

(E)-2-(4-chlorophenyl)-2,3-dihydro-3-[2-(trimethylammonium)ethylidene]-1H-pyrrolo[3,4-b]quinolin-1-one iodide (1028684-24-3) + N-methyl-N-(4-methoxyphenyl)amine (5961-59-1) → C27H22ClN3O2 (1028684-21-0)

Guidance literature:

With triphenylphosphine; palladium diacetate; In N,N-dimethyl-formamide; at 20 ℃; for 20h;

DOI:10.1016/j.bmc.2007.06.044

Reference yield:

(E)-2-(4-chlorophenyl)-2,3-dihydro-3-[2-(trimethylammonium)ethylidene]-1H-pyrrolo[3,4-b]quinolin-1-one iodide (1028684-24-3) + palladium diacetate (3375-31-3) → (E)-2-[2-(4-chlorophenyl)-1,2-dihydro-1-oxo-3H-pyrrolo[3,4-b]quinolin-3-ylidene]ethyl acetate (1028684-25-4)

Guidance literature:

With triphenylphosphine; In N,N-dimethyl-formamide; at 20 ℃; for 20h;

DOI:10.1016/j.bmc.2007.06.044

upstream raw materials:

(E)-2-(4-chlorophenyl)-2,3-dihydro-3-[2-(dimethylamino)ethylidene]-1H-pyrrolo[3,4-b]quinolin-1-one

methyl iodide

Downstream raw materials:

(E)-2-[2-(4-chlorophenyl)-1,2-dihydro-1-oxo-3H-pyrrolo[3,4-b]quinolin-3-ylidene]ethyl acetate

C₂₇H₂₂ClN₃O₂