3,3-di-p-tolyl-acrylic acid amide

Base Information

• Chemical Name: 3,3-di-p-tolyl-acrylic acid amide
• CAS No.: 93816-69-4
• Molecular Formula: C₁₇H₁₇NO
• Molecular Weight: 251.328
• Mol file: 93816-69-4.mol

Synonyms:3,3-di-p-tolyl-acrylic acid amide

Chemical Property of 3,3-di-p-tolyl-acrylic acid amide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 3,3-di-p-tolyl-acrylic acid amide

There total 2 articles about 3,3-di-p-tolyl-acrylic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-tolyl iodide (624-31-7) + 2-propenamide (79-06-1,12624-24-7,25038-45-3,27754-57-0,33338-03-3,39387-77-4,68247-81-4,9082-06-8,79079-15-5) → 3,3-di-p-tolyl-acrylic acid amide (93816-69-4)

Guidance literature:

4-tolyl iodide; 2-propenamide; With triethylamine; In acetonitrile; at 100 ℃;

4-tolyl iodide; With palladium diacetate; triethylamine; at 100 ℃;

DOI:10.1021/jo202427m

Reference yield:

oxalyl dichloride (79-37-8) + 1,1-di(p-tolyl)ethylene (2919-20-2) → 3,3-di-p-tolyl-acrylic acid amide (93816-69-4)

Guidance literature:

Behandeln des Reaktionsprodukts mit NH₃ in Aether;

DOI:10.1021/jo01118a012

Reference yield: 57.0%

3,3-di-p-tolyl-acrylic acid amide (93816-69-4) → 7-methyl-4-p-tolylquinolin-2(1H)-one (1361194-46-8)

Guidance literature:

With copper(l) iodide; potassium tert-butylate; triphenylphosphine; In o-xylene; at 100 ℃; for 24h;

DOI:10.1021/jo202427m

upstream raw materials:

oxalyl dichloride

1,1-di(p-tolyl)ethylene

4-tolyl iodide

2-propenamide

Downstream raw materials:

7-methyl-4-p-tolylquinolin-2(1H)-one