4-(3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione

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Chemical Name:4-(3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione
CAS No.:1383377-62-5
Molecular Formula:C₁₇H₁₁FN₄O₂
Molecular Weight:322.298
Hs Code.:

Synonyms:4-(3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione

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Chemical Property of 4-(3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione

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Technology Process of 4-(3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione

There total 11 articles about 4-(3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1383377-53-4
4-(3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl)furo[3,4-b]-pyridine-5,7-dione

: 1383377-62-5
4-(3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione

Guidance literature:: 4-(3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl)furo[3,4-b]-pyridine-5,7-dione; With ammonium hydroxide; In water; for 0.5h; Reflux;

With acetic anhydride; acetic acid; at 120 ℃;
DOI:10.1021/acschemneuro.7b00155

Reference yield:

: 1383377-50-1
3-fluoro-4-(3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl)-picolinonitrile

: 1383377-62-5
4-(3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione

Guidance literature:: Multi-step reaction with 4 steps

1.1: dimethyl sulfoxide / 2 h / 50 °C

2.1: potassium hydroxide; water / 24 h / 100 °C

3.1: acetic anhydride; acetic acid / 3 h / 110 °C

4.1: ammonium hydroxide / water / 0.5 h / Reflux

4.2: 2 h / 120 °C

With ammonium hydroxide; water; acetic anhydride; acetic acid; potassium hydroxide; In water; dimethyl sulfoxide;

Reference yield:

: 1383377-51-2
4-(3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl)pyridine-2,3-dicarbonitrile

: 1383377-62-5
4-(3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium hydroxide; water / 24 h / 100 °C

2.1: acetic anhydride; acetic acid / 3 h / 110 °C

3.1: ammonium hydroxide / water / 0.5 h / Reflux

3.2: 2 h / 120 °C

With ammonium hydroxide; water; acetic anhydride; acetic acid; potassium hydroxide; In water;