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1,4-Bis(maleimido)butane

Base Information
  • Chemical Name:1,4-Bis(maleimido)butane
  • CAS No.:28537-70-4
  • Molecular Formula:C12H12 N2 O4
  • Molecular Weight:248.23
  • Hs Code.:2925190090
  • European Community (EC) Number:634-780-4
  • NSC Number:44747
  • DSSTox Substance ID:DTXSID80286325
  • Nikkaji Number:J102.954A
  • Wikidata:Q27463107
  • ChEMBL ID:CHEMBL567436
  • Mol file:28537-70-4.mol
1,4-Bis(maleimido)butane

Synonyms:28537-70-4;1,4-Bis(maleimido)butane;1,4-BIS-MALEIMIDOBUTANE;1,1'-(Butane-1,4-diyl)bis(1H-pyrrole-2,5-dione);1H-Pyrrole-2,5-dione, 1,1'-(1,4-butanediyl)bis-;1,4-bismaleimidobutane;1-[4-(2,5-dioxopyrrol-1-yl)butyl]pyrrole-2,5-dione;N,N'-Tetramethylenebismaleimide;Tetramethylene-bismaleimide;CHEMBL567436;Maleimide, N,N'-tetramethylenedi-;MFCD01318342;1,1'-Butane-1,4-Diylbis(1h-Pyrrole-2,5-Dione);1-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butyl]-2,5-dihydro-1H-pyrrole-2,5-dione;1,4-Di(maleimido)butane;NSC44747;NSC 44747;LCZC785;SCHEMBL155748;N,N'-Tetramethylenedimaleimide;Maleimide,N'-tetramethylenedi-;BMB (1,4-bismaleimidobutane);DTXSID80286325;N,N'-(Tetramethylene)dimaleimide;N,N'-Tetramethylenebis(maleimide);BDBM50300350;NSC-44747;AKOS015898234;AS-67288;SY055318;B3805;FT-0663317;1,4-Di(maleimido)butane, >=99.0% (HPLC);1H-Pyrrole-2, 1,1'-(1,4-butanediyl)bis-;T70715;J-017117;Q27463107;(1-(4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butyl)-1H-maleimide);1,1 inverted exclamation mark -(Butane-1,4-diyl)bis(1H-pyrrole-2,5-dione)

Suppliers and Price of 1,4-Bis(maleimido)butane
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 1,4-Bis(maleimido)butane
  • 100mg
  • $ 110.00
  • TCI Chemical
  • 1,4-Bis(maleimido)butane >98.0%(HPLC)(N)
  • 1g
  • $ 392.00
  • TCI Chemical
  • 1,4-Bis(maleimido)butane >98.0%(HPLC)(N)
  • 100mg
  • $ 98.00
  • Sigma-Aldrich
  • 1,4-Di(maleimido)butane ≥99.0% (HPLC)
  • 100mg-f
  • $ 166.00
  • Medical Isotopes, Inc.
  • 1,4-Bis-maleimidobutane
  • 10 mg
  • $ 830.00
  • Crysdot
  • 1,1'-(Butane-1,4-diyl)bis(1H-pyrrole-2,5-dione) 97%
  • 1g
  • $ 651.00
  • Crysdot
  • 1,1'-(Butane-1,4-diyl)bis(1H-pyrrole-2,5-dione) 97%
  • 100mg
  • $ 162.00
  • Crysdot
  • 1,1'-(Butane-1,4-diyl)bis(1H-pyrrole-2,5-dione) 97%
  • 250mg
  • $ 260.00
  • Chem-Impex
  • 1,4-Bis-maleimidobutane,≥99%(NMR) ≥99%(NMR)
  • 100MG
  • $ 186.37
  • Chem-Impex
  • 1,4-Bis-maleimidobutane,99%(NMR) 99%(NMR)
  • 250MG
  • $ 308.00
Total 16 raw suppliers
Chemical Property of 1,4-Bis(maleimido)butane
Chemical Property:
  • Melting Point:196-197°C 
  • Boiling Point:450.3°Cat760mmHg 
  • PKA:-1.93±0.20(Predicted) 
  • Flash Point:219.1°C 
  • PSA:74.76000 
  • Density:1.388g/cm3 
  • LogP:-0.50760 
  • Storage Temp.:-20°C Freezer 
  • Solubility.:Chloroform 
  • XLogP3:-0.5
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:5
  • Exact Mass:248.07970687
  • Heavy Atom Count:18
  • Complexity:399
Purity/Quality:

97% *data from raw suppliers

1,4-Bis(maleimido)butane *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes:Xi 
  • Statements: 36/37/38 
  • Safety Statements: 26-36 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:C1=CC(=O)N(C1=O)CCCCN2C(=O)C=CC2=O
  • Uses A short, sulfhydryl reactive homobifunctional crosslinking reagent
Technology Process of 1,4-Bis(maleimido)butane

There total 2 articles about 1,4-Bis(maleimido)butane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With sodium hydrogencarbonate; In tetrahydrofuran; for 3h; Ambient temperature;
DOI:10.1021/jm00087a010
Guidance literature:
With N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide; at 20 ℃; chemoselective reaction;
DOI:10.1021/cc900141b
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