10-Hped

Base Information

• Chemical Name: 10-Hped
• CAS No.: 2135-57-1
• Molecular Formula: C18H24 O4
• Molecular Weight: 304.38
• Mol file: 2135-57-1.mol

Synonyms:Hydroperoxide,3,17-dioxoestr-4-en-10-yl (7CI)

Chemical Property of 10-Hped

Chemical Property:

• Vapor Pressure: 3.46E-12mmHg at 25°C
• Boiling Point: 502.2°C at 760 mmHg
• Flash Point: 183.2°C
• PSA: 63.60000
• Density: 1.25g/cm³
• LogP: 3.30950

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 10-Hped

There total 5 articles about 10-Hped which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

19-oxoandrostenedione (968-49-0) → 10β-hydroxy-19-norandrost-4-ene-3,17-dione (5189-96-8) + 10β-Hydroperoxy-Δ4-oestren-3,17-dion (2135-57-1)

Guidance literature:

With air; 2,2'-azobis(isobutyronitrile); In toluene; at 50 ℃; for 72h;

DOI:10.1039/c39890001699

Reference yield:

19-hydroxy-4-androstene-3,17-dione (510-64-5) → 10β-Hydroperoxy-Δ4-oestren-3,17-dion (2135-57-1)

Guidance literature:

Multi-step reaction with 2 steps

1: CrO₃, aq. H₂SO₄ / CHCl₃

2: O₂, AIBN

With chromium(VI) oxide; 2,2'-azobis(isobutyronitrile); sulfuric acid; oxygen; In chloroform;

Reference yield:

19-oxoandrostenedione (968-49-0) → 10β-Hydroperoxy-Δ4-oestren-3,17-dion (2135-57-1)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); oxygen;

upstream raw materials:

19-oxoandrostenedione

19-hydroxy-4-androstene-3,17-dione

Refernces

• 1、 Grinenko,Bayunova. "". . . Retrieved 1972.