dimethyl [(RS)-1-(benzyloxycarbonylamino)-3-(tert-butylsulfanyl)propyl]phosphonate

Base Information

Chemical Name:dimethyl [(RS)-1-(benzyloxycarbonylamino)-3-(tert-butylsulfanyl)propyl]phosphonate
CAS No.:1367824-57-4
Molecular Formula:C₁₇H₂₈NO₅PS
Molecular Weight:389.453
Hs Code.:

Synonyms:dimethyl [(RS)-1-(benzyloxycarbonylamino)-3-(tert-butylsulfanyl)propyl]phosphonate

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Chemical Property of dimethyl [(RS)-1-(benzyloxycarbonylamino)-3-(tert-butylsulfanyl)propyl]phosphonate

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Technology Process of dimethyl [(RS)-1-(benzyloxycarbonylamino)-3-(tert-butylsulfanyl)propyl]phosphonate

There total 3 articles about dimethyl [(RS)-1-(benzyloxycarbonylamino)-3-(tert-butylsulfanyl)propyl]phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 1367824-44-9
diphenyl [(RS)-1-(benzyloxycarbonylamino)-3-(tert-butylsulfanyl)propyl]phosphonate

: 124-41-4
sodium methylate

: 1367824-57-4
dimethyl [(RS)-1-(benzyloxycarbonylamino)-3-(tert-butylsulfanyl)propyl]phosphonate

Guidance literature:: With methanol; In 1,4-dioxane; at 20 ℃;

Reference yield: 45.0%

: 621-84-1
O-benzyl carbamate

: 77275-25-3
3-(tert-butylsulfanyl)propanal

: 868-85-9
Dimethyl phosphite

: 1367824-57-4
dimethyl [(RS)-1-(benzyloxycarbonylamino)-3-(tert-butylsulfanyl)propyl]phosphonate

Guidance literature:: With acetyl chloride; at 0 - 20 ℃;

Reference yield:

: 621-84-1
O-benzyl carbamate

: 77275-25-3
3-(tert-butylsulfanyl)propanal

: 1367824-57-4
dimethyl [(RS)-1-(benzyloxycarbonylamino)-3-(tert-butylsulfanyl)propyl]phosphonate

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / 1 h / 80 °C

2: methanol / 1,4-dioxane / 20 °C

With methanol; acetic acid; In 1,4-dioxane;