4-Methylbenzamidine hydrochloride

Base Information

• Chemical Name: 4-Methylbenzamidine hydrochloride
• CAS No.: 6326-27-8
• Deprecated CAS: 39800-79-8
• Molecular Formula: C8H10N2^.HCl
• Molecular Weight: 170.642
• Hs Code.: 2925290090
• European Community (EC) Number: 672-862-1
• NSC Number: 30577
• UNII: 3AD6HT2FNA
• DSSTox Substance ID: DTXSID80212644
• Mol file: 6326-27-8.mol

Synonyms:6326-27-8;4-Methylbenzamidine hydrochloride;4-methylbenzimidamide hydrochloride;4-Methylbenzene-1-carboximidamide hydrochloride;4-Toluamidine hydrochloride;4-Methyl-benzamidine hydrochloride;Benzenecarboximidamide, 4-methyl-, monohydrochloride;4-methylbenzenecarboximidamide hydrochloride;4-Toluamidine HCl;p-Toluamidine, monohydrochloride;4-methylbenzamidine HCl;4-METHYLBENZIMIDAMIDE, HCL;NSC 30577;4-methylbenzenecarboximidamide;hydrochloride;4-Methylbenzenecarboximidamide monohydrochloride;NSC-30577;3AD6HT2FNA;p-toluamidine hydrochloride;C8H10N2.ClH;p-toluamidine monohydrochloride;SCHEMBL1019464;p-methylbenzamidine hydrochloride;4-methylbenzimidamidehydrochloride;DTXSID80212644;4-methylbenzamidine hydro-chloride;NSC30577;AM9931;MFCD00040183;AKOS015890849;AB01792;CS-W010775;PS-8694;LS-154009;FT-0619061;M2714;4-methylbenzamidine hydrochloride, AldrichCPR;EN300-73561;F11800;J-515774;Benzenecarboximidamide, 4-methyl-, hydrochloride (1:1);Z1405445841;Benzenecarboximidamide, 4-methyl-, monohydrochloride (9CI)

Chemical Property of 4-Methylbenzamidine hydrochloride

Chemical Property:

• Vapor Pressure: 0.0884mmHg at 25°C
• Melting Point: 211-214 ºC
• Boiling Point: 225°C at 760 mmHg
• Flash Point: 89.9°C
• PSA: 49.87000
• LogP: 2.88110
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive.: Hygroscopic
• Solubility.: soluble in Methanol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 170.0610761
• Heavy Atom Count: 11
• Complexity: 123

Purity/Quality:

97% ^*data from raw suppliers

4-Methylbenzimidamidehydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)C(=N)N.Cl
• Uses: 4-Methylbenzimidamide, HCl

Technology Process of 4-Methylbenzamidine hydrochloride

There total 6 articles about 4-Methylbenzamidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

→ p-methylbenzamidine hydrochloride (6326-27-8)

Guidance literature:

Reference yield: 79.0%

para-methylbenzonitrile (104-85-8) → p-methylbenzamidine hydrochloride (6326-27-8)

Guidance literature:

DOI:10.1071/CH9850825

Reference yield: 71.0%

ethyl 4-methylbenzimidate hydrochloride (43002-64-8) → p-methylbenzamidine hydrochloride (6326-27-8)

Guidance literature:

With ammonia; In ethanol;

DOI:10.1134/S1070428012020091

upstream raw materials:

para-methylbenzonitrile

hexamethyldisilazan

p-toluamidoxime

ethyl 4-methylbenzimidate hydrochloride

Downstream raw materials:

4,6-bis(4-methylphenyl)-2-oxo-2,3-dihydro-sym-triazine

6-methyl-2-(4-methylphenyl)pyrimidin-4-one

6-phenyl-2-p-tolyl-3H-pyrimidin-4-one

4,6-dimethyl-2-(p-tolyl)pyrimidine