4-methylbenzenesulfonyl N'-(5-nitrofuran-2-ylmethylene)hydrazide

Base Information

• Chemical Name: 4-methylbenzenesulfonyl N'-(5-nitrofuran-2-ylmethylene)hydrazide
• CAS No.: 13777-58-7
• Molecular Formula: C₁₂H₁₁N₃O₅S
• Molecular Weight: 309.302
• Mol file: 13777-58-7.mol

Synonyms:4-methylbenzenesulfonyl N'-(5-nitrofuran-2-ylmethylene)hydrazide

Chemical Property of 4-methylbenzenesulfonyl N'-(5-nitrofuran-2-ylmethylene)hydrazide

Chemical Property:

Purity/Quality:

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Technology Process of 4-methylbenzenesulfonyl N'-(5-nitrofuran-2-ylmethylene)hydrazide

There total 3 articles about 4-methylbenzenesulfonyl N'-(5-nitrofuran-2-ylmethylene)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.94%

5-nitrofurane-2-carboxaldehyde (698-63-5) + toluene-4-sulfonic acid hydrazide (1576-35-8) → 4-methylbenzenesulfonyl N'-(5-nitrofuran-2-ylmethylene)hydrazide (13777-58-7)

Guidance literature:

In ethanol; for 2h; Reflux;

DOI:10.14233/ajchem.2015.18896

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → 4-methylbenzenesulfonyl N'-(5-nitrofuran-2-ylmethylene)hydrazide (13777-58-7)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / 0.5 h / Reflux

2: ethanol / 2 h / Reflux

With hydrazine hydrate; In ethanol;

DOI:10.14233/ajchem.2015.18896

Reference yield:

→ 4-methylbenzenesulfonyl N'-(5-nitrofuran-2-ylmethylene)hydrazide (13777-58-7)

Guidance literature:

Tosylhydrazid, 5-Nitrofurfurol;

DOI:10.1002/jps.2600680745

upstream raw materials:

5-nitrofurane-2-carboxaldehyde

toluene-4-sulfonic acid hydrazide

p-toluenesulfonyl chloride

Downstream raw materials:

2-amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole