Technology Process of N1,N9-bis(2,3-dihydroxybenzoyl)bis(4-aminobutyl)amine hydrobromide
There total 4 articles about N1,N9-bis(2,3-dihydroxybenzoyl)bis(4-aminobutyl)amine hydrobromide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
boron tribromide;
In
dichloromethane;
for 15h;
0 deg C to room temperature;
DOI:10.1021/jo00335a041
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 97 percent / triethylamine / CH2Cl2 / 0 deg C to room temperature
2: 99 percent / 1) H2, 2) NaOMe / 1) PdCl2 / 1) glacial acetic acid, room temperature, 2) MeOH, 30 min
3: 93 percent / BBr3 / CH2Cl2 / 15 h / 0 deg C to room temperature
With
hydrogen; sodium methylate; boron tribromide; triethylamine;
palladium dichloride;
In
dichloromethane;
DOI:10.1021/jo00335a041
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 66 percent / LiAlH4, AlCl3
2: 97 percent / triethylamine / CH2Cl2 / 0 deg C to room temperature
3: 99 percent / 1) H2, 2) NaOMe / 1) PdCl2 / 1) glacial acetic acid, room temperature, 2) MeOH, 30 min
4: 93 percent / BBr3 / CH2Cl2 / 15 h / 0 deg C to room temperature
With
lithium aluminium tetrahydride; aluminium trichloride; hydrogen; sodium methylate; boron tribromide; triethylamine;
palladium dichloride;
In
dichloromethane;
DOI:10.1021/jo00335a041
