(R)-6-(3-bromobenzenesulfonyl)-1-(4-fluorophenyl)-4a-hydroxymethyl-4,4a,5,6,7,8-hexahydro-1H-1,2,6-triaza-cyclopenta[b]naphthalene

Base Information

Chemical Name:(R)-6-(3-bromobenzenesulfonyl)-1-(4-fluorophenyl)-4a-hydroxymethyl-4,4a,5,6,7,8-hexahydro-1H-1,2,6-triaza-cyclopenta[b]naphthalene
CAS No.:1452782-95-4
Molecular Formula:C₂₃H₂₁BrFN₃O₃S
Molecular Weight:518.406
Hs Code.:

Synonyms:(R)-6-(3-bromobenzenesulfonyl)-1-(4-fluorophenyl)-4a-hydroxymethyl-4,4a,5,6,7,8-hexahydro-1H-1,2,6-triaza-cyclopenta[b]naphthalene

Suppliers and Price of (R)-6-(3-bromobenzenesulfonyl)-1-(4-fluorophenyl)-4a-hydroxymethyl-4,4a,5,6,7,8-hexahydro-1H-1,2,6-triaza-cyclopenta[b]naphthalene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-6-(3-bromobenzenesulfonyl)-1-(4-fluorophenyl)-4a-hydroxymethyl-4,4a,5,6,7,8-hexahydro-1H-1,2,6-triaza-cyclopenta[b]naphthalene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-6-(3-bromobenzenesulfonyl)-1-(4-fluorophenyl)-4a-hydroxymethyl-4,4a,5,6,7,8-hexahydro-1H-1,2,6-triaza-cyclopenta[b]naphthalene

There total 3 articles about (R)-6-(3-bromobenzenesulfonyl)-1-(4-fluorophenyl)-4a-hydroxymethyl-4,4a,5,6,7,8-hexahydro-1H-1,2,6-triaza-cyclopenta[b]naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1452782-96-5
(R)-6-(3-bromobenzenesulfonyl)-1-(4-fluorophenyl)-1,4,5,6,7,8-hexahydro-1H-1,2,6-triaza-cyclopenta[b]naphthalene-4a-carboxylic acid methyl ester

: 1452782-95-4
(R)-6-(3-bromobenzenesulfonyl)-1-(4-fluorophenyl)-4a-hydroxymethyl-4,4a,5,6,7,8-hexahydro-1H-1,2,6-triaza-cyclopenta[b]naphthalene

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane; toluene; at -78 - 10 ℃; Inert atmosphere;

Reference yield:

: 2905-24-0
3-Bromobenzenesulfonyl chloride

: 1452782-95-4
(R)-6-(3-bromobenzenesulfonyl)-1-(4-fluorophenyl)-4a-hydroxymethyl-4,4a,5,6,7,8-hexahydro-1H-1,2,6-triaza-cyclopenta[b]naphthalene

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride / water; 1,4-dioxane / 1.25 h

1.2: 16 h / 20 °C

2.1: diisobutylaluminium hydride / dichloromethane; toluene / -78 - 10 °C / Inert atmosphere

With hydrogenchloride; diisobutylaluminium hydride; In 1,4-dioxane; dichloromethane; water; toluene;

Reference yield:

: 864972-21-4
6-tert-butyl 4a-methyl (4aR)-1-(4-fluorophenyl)-4a,5,7,8-tetrahydro-1H-pyrazolo[3,4-g]isoquinoline-4a,6(4H)-dicarboxylate

: 1452782-95-4
(R)-6-(3-bromobenzenesulfonyl)-1-(4-fluorophenyl)-4a-hydroxymethyl-4,4a,5,6,7,8-hexahydro-1H-1,2,6-triaza-cyclopenta[b]naphthalene

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride / water; 1,4-dioxane / 1.25 h

1.2: 16 h / 20 °C

2.1: diisobutylaluminium hydride / dichloromethane; toluene / -78 - 10 °C / Inert atmosphere

With hydrogenchloride; diisobutylaluminium hydride; In 1,4-dioxane; dichloromethane; water; toluene;