(R)-N-[2-(3-aminosulphonyl-4-methoxyphenyl)-1-methylethyl]-2-(2-ethoxyphenoxy)-acetamide

Base Information

Chemical Name:(R)-N-[2-(3-aminosulphonyl-4-methoxyphenyl)-1-methylethyl]-2-(2-ethoxyphenoxy)-acetamide
CAS No.:133261-17-3
Molecular Formula:C₂₀H₂₆N₂O₆S
Molecular Weight:422.502
Hs Code.:
European Community (EC) Number:682-877-5

Synonyms:133261-17-3;SCHEMBL4777691;IPHNYXYPQJHUIV-CQSZACIVSA-N;(R)-N-[2-(3-aminosulphonyl-4-methoxyphenyl)-1-methylethyl]-2-(2-ethoxyphenoxy)-acetamide;(R)-2-(2-ethoxyphenoxy)-N-[2-(4-methoxy-3-aminosulfonyl-phenyl)-1-methyl-ethyl]-acetamide;2-(2-Ethoxyphenoxy)-N-[(1R)-2-(4-methoxy-3-sulfamoylphenyl)-1-methylethyl]acetamide;N-Des(2-(2-ethoxy)phenoxy)ethyl), N-(2-(2-ethoxy)phenoxy)acetyl) Tamsulosin

Suppliers and Price of (R)-N-[2-(3-aminosulphonyl-4-methoxyphenyl)-1-methylethyl]-2-(2-ethoxyphenoxy)-acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of (R)-N-[2-(3-aminosulphonyl-4-methoxyphenyl)-1-methylethyl]-2-(2-ethoxyphenoxy)-acetamide

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:10
Exact Mass:422.15115773
Heavy Atom Count:29
Complexity:609

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC1=CC=CC=C1OCC(=O)NC(C)CC2=CC(=C(C=C2)OC)S(=O)(=O)N
Isomeric SMILES:CCOC1=CC=CC=C1OCC(=O)N[C@H](C)CC2=CC(=C(C=C2)OC)S(=O)(=O)N

Technology Process of (R)-N-[2-(3-aminosulphonyl-4-methoxyphenyl)-1-methylethyl]-2-(2-ethoxyphenoxy)-acetamide

There total 3 articles about (R)-N-[2-(3-aminosulphonyl-4-methoxyphenyl)-1-methylethyl]-2-(2-ethoxyphenoxy)-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.8%

: 94-71-3
2-Ethoxyphenol

: (R)-2-bromo-N-[2-(4-methoxy-3-aminosulfonyl-phenyl)-1-methyl-ethyl]-acetamide

: 133261-17-3
(R)-2-(2-ethoxyphenoxy)-N-[2-(4-methoxy-3-aminosulfonyl-phenyl)-1-methyl-ethyl]-acetamide

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at 25 ℃; for 1h;

Reference yield: 77.0%

: methyl 2-ethoxyphenoxyacetate

: 112101-81-2
5-((R)-2-amino-1-propyl)-2-methoxybenzenesulphonamide

: 133261-17-3
(R)-2-(2-ethoxyphenoxy)-N-[2-(4-methoxy-3-aminosulfonyl-phenyl)-1-methyl-ethyl]-acetamide

Guidance literature:: 5-((R)-2-amino-1-propyl)-2-methoxybenzenesulphonamide; With diisobutylaluminium hydride; In tetrahydrofuran; at 0 - 25 ℃; for 1.08333h;

methyl 2-ethoxyphenoxyacetate; In tetrahydrofuran; toluene; at 20 - 25 ℃; for 16h;

Reference yield: 73.0%

: 94-71-3
2-Ethoxyphenol

: (R)-2-chloro-N-[2-(4-methoxy-3-aminosulfonyl-phenyl)-1-methyl-ethyl]-acetamide

: 133261-17-3
(R)-2-(2-ethoxyphenoxy)-N-[2-(4-methoxy-3-aminosulfonyl-phenyl)-1-methyl-ethyl]-acetamide

Guidance literature:: 2-Ethoxyphenol; With sodium hydroxide; In water; at 65 - 70 ℃; for 0.25h;

(R)-2-chloro-N-[2-(4-methoxy-3-aminosulfonyl-phenyl)-1-methyl-ethyl]-acetamide; In water; at 65 - 70 ℃; for 1h;