2-((2-(4-chlorophenyl)hydrazinyl)methylene)-5,5-dimethylcyclohexane-1,3-dione

Base Information

• Chemical Name: 2-((2-(4-chlorophenyl)hydrazinyl)methylene)-5,5-dimethylcyclohexane-1,3-dione
• CAS No.: 308248-82-0
• Molecular Formula: C₁₅H₁₇ClN₂O₂
• Molecular Weight: 292.765
• Mol file: 308248-82-0.mol

Synonyms:2-((2-(4-chlorophenyl)hydrazinyl)methylene)-5,5-dimethylcyclohexane-1,3-dione

Chemical Property of 2-((2-(4-chlorophenyl)hydrazinyl)methylene)-5,5-dimethylcyclohexane-1,3-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-((2-(4-chlorophenyl)hydrazinyl)methylene)-5,5-dimethylcyclohexane-1,3-dione

There total 4 articles about 2-((2-(4-chlorophenyl)hydrazinyl)methylene)-5,5-dimethylcyclohexane-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-chlorophenylhydrazine hydrochloride (1073-70-7) + potassium salt of 2-formyldimedone → 2-((2-(4-chlorophenyl)hydrazinyl)methylene)-5,5-dimethylcyclohexane-1,3-dione (308248-82-0)

Guidance literature:

In water; at 80 - 90 ℃;

DOI:10.1007/BF02269546

Reference yield: 71.0%

4-chlorophenylhydrazine hydrochloride (1073-70-7) + dimedone (126-81-8) + N,N-dimethyl-formamide dimethyl acetal (4637-24-5) → 2-((2-(4-chlorophenyl)hydrazinyl)methylene)-5,5-dimethylcyclohexane-1,3-dione (308248-82-0)

Guidance literature:

at 70 ℃; for 0.116667h;

DOI:10.3184/174751914X13940194215183

Reference yield: 65.0%

2-dimethylaminomethylene-5,5-dimethylcyclohexane-1,3-dione (75039-59-7) + N-4-chlorophenylhydrazine (1073-69-4) → 2-((2-(4-chlorophenyl)hydrazinyl)methylene)-5,5-dimethylcyclohexane-1,3-dione (308248-82-0)

Guidance literature:

for 0.0833333h; regioselective reaction; Heating;

DOI:10.1016/j.molstruc.2020.129710

upstream raw materials:

4-chlorophenylhydrazine hydrochloride

dimedone

N,N-dimethyl-formamide dimethyl acetal

2-dimethylaminomethylene-5,5-dimethylcyclohexane-1,3-dione

Downstream raw materials:

1-(4-chlorophenyl)-6,6-dimethyl-4,5-dioxo-4,5,6,7-tetrahydroindazole