allyl 3-O-(3-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl)-2-O-benzyl-α-L-fucopyranoside

Base Information

• Chemical Name: allyl 3-O-(3-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl)-2-O-benzyl-α-L-fucopyranoside
• CAS No.: 488719-75-1
• Molecular Formula: C₃₆H₄₂O₁₀
• Molecular Weight: 634.723
• Mol file: 488719-75-1.mol

Synonyms:allyl 3-O-(3-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl)-2-O-benzyl-α-L-fucopyranoside

Chemical Property of allyl 3-O-(3-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl)-2-O-benzyl-α-L-fucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of allyl 3-O-(3-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl)-2-O-benzyl-α-L-fucopyranoside

There total 2 articles about allyl 3-O-(3-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl)-2-O-benzyl-α-L-fucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

benzoyl chloride (98-88-4) + allyl 3-O-(2-O-benzyl-α-L-fucopyranosyl)-2-O-benzyl-α-L-fucopyranoside (488719-74-0) → allyl 3-O-(3-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl)-2-O-benzyl-α-L-fucopyranoside (488719-75-1)

Guidance literature:

allyl 3-O-(2-O-benzyl-α-L-fucopyranosyl)-2-O-benzyl-α-L-fucopyranoside; With di(n-butyl)tin oxide; In toluene; Heating;

benzoyl chloride; In toluene; at 20 ℃; for 3h;

DOI:10.1081/CAR-120013500

Reference yield:

C43H45O14S(1-)*Na(1+) → allyl 3-O-(3-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl)-2-O-benzyl-α-L-fucopyranoside (488719-75-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 85 percent / MeONa / methanol / 1 h / 20 °C

2.1: Bu₂SnO / toluene / Heating

2.2: 77 percent / toluene / 3 h / 20 °C

With sodium methylate; di(n-butyl)tin oxide; In methanol; toluene;

DOI:10.1081/CAR-120013500

Reference yield:

allyl 3-O-(3-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl)-2-O-benzyl-α-L-fucopyranoside (488719-75-1) → Benzoic acid (2S,3S,4S,5R,6S)-2-((2R,3S,4S,5R,6S)-2-allyloxy-3-benzyloxy-6-methyl-5-sulfooxy-tetrahydro-pyran-4-yloxy)-3-benzyloxy-6-methyl-5-sulfooxy-tetrahydro-pyran-4-yl ester

Guidance literature:

With pyridine-SO₃ complex; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

DOI:10.1081/CAR-120013500

upstream raw materials:

benzoyl chloride

allyl 3-O-(2-O-benzyl-α-L-fucopyranosyl)-2-O-benzyl-α-L-fucopyranoside