dimethyl (4-dimethoxymethyl-3-hydroxy-2-methyl-6-benzylpyrid-5-yl)methylphosphonate

Base Information

Chemical Name:dimethyl (4-dimethoxymethyl-3-hydroxy-2-methyl-6-benzylpyrid-5-yl)methylphosphonate
CAS No.:860462-18-6
Molecular Formula:C₁₉H₂₆NO₆P
Molecular Weight:395.392
Hs Code.:

Synonyms:dimethyl (4-dimethoxymethyl-3-hydroxy-2-methyl-6-benzylpyrid-5-yl)methylphosphonate

Suppliers and Price of dimethyl (4-dimethoxymethyl-3-hydroxy-2-methyl-6-benzylpyrid-5-yl)methylphosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of dimethyl (4-dimethoxymethyl-3-hydroxy-2-methyl-6-benzylpyrid-5-yl)methylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of dimethyl (4-dimethoxymethyl-3-hydroxy-2-methyl-6-benzylpyrid-5-yl)methylphosphonate

There total 4 articles about dimethyl (4-dimethoxymethyl-3-hydroxy-2-methyl-6-benzylpyrid-5-yl)methylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 883747-34-0
6-benzyl-5-chloromethyl-4-dimethoxymethyl-2-methyl-pyridin-3-ol

: 121-45-9
phosphorous acid trimethyl ester

: 860462-18-6
dimethyl (4-dimethoxymethyl-3-hydroxy-2-methyl-6-benzylpyrid-5-yl)methylphosphonate

Guidance literature:: at 65 - 70 ℃; for 72h;
DOI:10.1016/j.bcp.2005.04.021

Reference yield:

: 860462-17-5
6-(benzyl)pyridoxal-4-dimethylacetal

: 860462-18-6
dimethyl (4-dimethoxymethyl-3-hydroxy-2-methyl-6-benzylpyrid-5-yl)methylphosphonate

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / thionyl chloride / benzene / 0.08 h

2: 38 percent / 72 h / 65 - 70 °C

With thionyl chloride; In benzene; 1: chlorination / 2: phosphorylation; Arbuzov reaction;
DOI:10.1016/j.bcp.2005.04.021

Reference yield:

: 860462-16-4
2,2-dimethyl-propionic acid 4-benzyl-1-hydroxy-6-methyl-1,3-dihydro-furo[3,4-c]pyridin-7-yl ester

: 860462-18-6
dimethyl (4-dimethoxymethyl-3-hydroxy-2-methyl-6-benzylpyrid-5-yl)methylphosphonate

Guidance literature:: Multi-step reaction with 3 steps

1: 68 percent / KOH / 0.17 h

2: 100 percent / thionyl chloride / benzene / 0.08 h

3: 38 percent / 72 h / 65 - 70 °C

With potassium hydroxide; thionyl chloride; In benzene; 1: ring cleavage; methylation / 2: chlorination / 3: phosphorylation; Arbuzov reaction;
DOI:10.1016/j.bcp.2005.04.021