4-(4-toluenesulfonylureido-D-phenylalanylamido)benzenesulfonyl-O-methylisourea

Base Information

Chemical Name:4-(4-toluenesulfonylureido-D-phenylalanylamido)benzenesulfonyl-O-methylisourea
CAS No.:276245-67-1
Molecular Formula:C₂₅H₂₇N₅O₇S₂
Molecular Weight:573.651
Hs Code.:

Synonyms:4-(4-toluenesulfonylureido-D-phenylalanylamido)benzenesulfonyl-O-methylisourea

Suppliers and Price of 4-(4-toluenesulfonylureido-D-phenylalanylamido)benzenesulfonyl-O-methylisourea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-(4-toluenesulfonylureido-D-phenylalanylamido)benzenesulfonyl-O-methylisourea

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(4-toluenesulfonylureido-D-phenylalanylamido)benzenesulfonyl-O-methylisourea

There total 5 articles about 4-(4-toluenesulfonylureido-D-phenylalanylamido)benzenesulfonyl-O-methylisourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-56-1
methanol

: 1027090-53-4
C₂₄H₂₃N₅O₆S₂

: 276245-67-1
4-(4-toluenesulfonylureido-D-phenylalanylamido)benzenesulfonyl-O-methylisourea

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 4 ℃; for 96h;
DOI:10.1021/jm9903693

Reference yield:

: 116-47-2
sulfanilylcyanamide

: 276245-67-1
4-(4-toluenesulfonylureido-D-phenylalanylamido)benzenesulfonyl-O-methylisourea

Guidance literature:: Multi-step reaction with 2 steps

1: EDCI*HCl; Et₃N / acetonitrile / 16 h / 4 °C

2: HCl(g) / dioxane / 96 h / 4 °C

With hydrogenchloride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In 1,4-dioxane; acetonitrile; 1: Condensation / 2: Addition;
DOI:10.1021/jm9903693

Reference yield:

: 673-06-3,25191-15-5,658-69-5,67675-33-6
D-(R)-phenylalanine

: 276245-67-1
4-(4-toluenesulfonylureido-D-phenylalanylamido)benzenesulfonyl-O-methylisourea

Guidance literature:: Multi-step reaction with 3 steps

1: acetone / 4 h / 4 °C

2: EDCI*HCl; Et₃N / acetonitrile / 16 h / 4 °C

3: HCl(g) / dioxane / 96 h / 4 °C

With hydrogenchloride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In 1,4-dioxane; acetone; acetonitrile; 1: Condensation / 2: Condensation / 3: Addition;
DOI:10.1021/jm9903693