2-chloro-4-(4-tertbutylphenylamino)-6-(4-iodophenylamino)-1,3,5-triazine

Base Information

• Chemical Name: 2-chloro-4-(4-tertbutylphenylamino)-6-(4-iodophenylamino)-1,3,5-triazine
• CAS No.: 1005346-55-3
• Molecular Formula: C₁₉H₁₉ClIN₅
• Molecular Weight: 479.751
• Mol file: 1005346-55-3.mol

Synonyms:2-chloro-4-(4-tertbutylphenylamino)-6-(4-iodophenylamino)-1,3,5-triazine

Chemical Property of 2-chloro-4-(4-tertbutylphenylamino)-6-(4-iodophenylamino)-1,3,5-triazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-chloro-4-(4-tertbutylphenylamino)-6-(4-iodophenylamino)-1,3,5-triazine

There total 2 articles about 2-chloro-4-(4-tertbutylphenylamino)-6-(4-iodophenylamino)-1,3,5-triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4-tert-butylphenyl)-(4,6-dichloro-[1,3,5]triazin-2-yl)-amine (146887-20-9) + p-aminoiodobenzene (540-37-4) → 2-chloro-4-(4-tertbutylphenylamino)-6-(4-iodophenylamino)-1,3,5-triazine (1005346-55-3)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 50 ℃; for 1h;

DOI:10.3184/030823407X215636

Reference yield:

4-tert-Butylaniline (769-92-6) → 2-chloro-4-(4-tertbutylphenylamino)-6-(4-iodophenylamino)-1,3,5-triazine (1005346-55-3)

Guidance literature:

Multi-step reaction with 2 steps

1: N,N-diisopropylethylamine / tetrahydrofuran / 20 - 50 °C

2: 2.38 g / N,N-diisopropylethylamine / tetrahydrofuran / 1 h / 50 °C

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran;

DOI:10.3184/030823407X215636

Reference yield: 46.0%

2-chloro-4-(4-tertbutylphenylamino)-6-(4-iodophenylamino)-1,3,5-triazine (1005346-55-3) → 2-amino-4-(4-tertbutylphenylamino)-6-(4-iodophenylamino)-1,3,5-triazine (1005346-56-4)

Guidance literature:

With ammonium hydroxide; In tetrahydrofuran; at 100 ℃; for 3h;

DOI:10.3184/030823407X215636

upstream raw materials:

(4-tert-butylphenyl)-(4,6-dichloro-[1,3,5]triazin-2-yl)-amine

p-aminoiodobenzene

4-tert-Butylaniline

Downstream raw materials:

2-amino-4-(4-tertbutylphenylamino)-6-(4-iodophenylamino)-1,3,5-triazine

2-amino-4-(4-tertbutylphenylamino)-6-(4-ethynylphenylamino)-1,3,5-triazine

2-amino-4-(4-tertbutylphenylamino)-6-[4-(trimethylsilylethynyl)phenylamino]-1,3,5-triazine