N-(2-Iodophenyl)Acrylamide

Base Information

• Chemical Name: N-(2-Iodophenyl)Acrylamide
• CAS No.: 192190-12-8
• Molecular Formula: C₉H₈INO
• Molecular Weight: 273.073
• Mol file: 192190-12-8.mol

Synonyms:N-(2-iodophenyl)-2-propenamide

Chemical Property of N-(2-Iodophenyl)Acrylamide

Chemical Property:

• Boiling Point: 369.4±34.0 °C(Predicted)
• PKA: 12.85±0.70(Predicted)
• Density: 1.748±0.06 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

N-(2-Iodophenyl)acrylamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-Iodophenyl)Acrylamide

There total 2 articles about N-(2-Iodophenyl)Acrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-iodophenylamine (615-43-0) + acryloyl chloride (814-68-6,25189-84-8) → N-(2-iodophenyl)-2-propenamide (192190-12-8)

Guidance literature:

In diethyl ether; for 1h; Ambient temperature;

DOI:10.1016/S0040-4020(97)00495-X

Reference yield:

2-iodophenylamine (615-43-0) + acrylic acid (79-10-7) → N-(2-iodophenyl)-2-propenamide (192190-12-8)

Guidance literature:

With iodine; triethylamine; phosphorous acid trimethyl ester; In dichloromethane; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1039/c5cc06329a

Reference yield: 70.0%

N-(2-iodophenyl)-2-propenamide (192190-12-8) + p-toluenesulfonyl chloride (98-59-9) → 2-iodo-N-(2-iodophenyl)-3-tosylpropanamide

Guidance literature:

With cetyltrimethylammonim bromide; acetic acid; sodium iodide; In water; at 20 ℃; for 15h; regioselective reaction; Inert atmosphere; Irradiation; Micellar solution; Green chemistry;

DOI:10.1039/d1gc00956g

upstream raw materials:

2-iodophenylamine

acryloyl chloride

acrylic acid

Downstream raw materials:

1H-Pyrrole-3-carboxylic acid (2-iodo-phenyl)-methyl-amide

3-[(2-Iodo-phenyl)-methyl-carbamoyl]-pyrrole-1-carboxylic acid tert-butyl ester

N-{2-[(trimethylsilanyl)ethynyl]phenyl}acrylamide