(1R,2R)-ethyl 1,2-bis(hydroxymethyl)cyclopropanecarboxylate

Base Information

Chemical Name:(1R,2R)-ethyl 1,2-bis(hydroxymethyl)cyclopropanecarboxylate
CAS No.:144985-81-9
Molecular Formula:C₈H₁₄O₄
Molecular Weight:174.197
Hs Code.:
Mol file:144985-81-9.mol

Synonyms:ethyl (1R,2R)-1,2-bis(hydroxymethyl)-1-cyclopropanecarboxylate

Suppliers and Price of (1R,2R)-ethyl 1,2-bis(hydroxymethyl)cyclopropanecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 4 raw suppliers

Chemical Property of (1R,2R)-ethyl 1,2-bis(hydroxymethyl)cyclopropanecarboxylate

Chemical Property:

Boiling Point:276.4±5.0 °C(Predicted)
PKA:15.10±0.10(Predicted)
Density:1.218±0.06 g/cm3(Predicted)

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of (1R,2R)-ethyl 1,2-bis(hydroxymethyl)cyclopropanecarboxylate

There total 4 articles about (1R,2R)-ethyl 1,2-bis(hydroxymethyl)cyclopropanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 145032-58-2
ethyl (1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate

: 144985-81-9
ethyl (1R,2R)-1,2-bis(hydroxymethyl)-1-cyclopropanecarboxylate

Guidance literature:: With sodium tetrahydroborate; In ethanol; at 0 ℃;
DOI:10.1080/15257770.2019.1625380

Reference yield: 72.0%

: C₈H₁₀O₄

: 144985-81-9
ethyl (1R,2R)-1,2-bis(hydroxymethyl)-1-cyclopropanecarboxylate

Guidance literature:: With sodium tetrahydroborate; ethanol; at 20 ℃; for 2h; Concentration;

Reference yield:

: 105-53-3
diethyl malonate

: 144985-81-9
ethyl (1R,2R)-1,2-bis(hydroxymethyl)-1-cyclopropanecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium / ethanol / 12 h / 0 - 20 °C / Reflux

2: sodium tetrahydroborate / ethanol / 5 h / 0 - 20 °C

With sodium tetrahydroborate; sodium; In ethanol;
DOI:10.1021/ol300728a