methyl 2-{(S)-[N-benzyl-N-((S)-1-phenylethyl)amino]phenylmethyl}acrylate

Base Information

Chemical Name:methyl 2-{(S)-[N-benzyl-N-((S)-1-phenylethyl)amino]phenylmethyl}acrylate
CAS No.:950580-16-2
Molecular Formula:C₂₆H₂₇NO₂
Molecular Weight:385.506
Hs Code.:

Synonyms:methyl 2-{(S)-[N-benzyl-N-((S)-1-phenylethyl)amino]phenylmethyl}acrylate

Suppliers and Price of methyl 2-{(S)-[N-benzyl-N-((S)-1-phenylethyl)amino]phenylmethyl}acrylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2-{(S)-[N-benzyl-N-((S)-1-phenylethyl)amino]phenylmethyl}acrylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2-{(S)-[N-benzyl-N-((S)-1-phenylethyl)amino]phenylmethyl}acrylate

There total 3 articles about methyl 2-{(S)-[N-benzyl-N-((S)-1-phenylethyl)amino]phenylmethyl}acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: C₂₆H₂₉NO₃

: 950580-16-2
methyl 2-{(S)-[N-benzyl-N-((S)-1-phenylethyl)amino]phenylmethyl}acrylate

Guidance literature:: With methanesulfonyl chloride; In 1,4-dioxane; at 60 ℃; for 16h;
DOI:10.1016/j.tetasy.2007.06.010

Reference yield: 48.0%

: 67-56-1
methanol

: lithium N-benzyl-N-((S)-1-phenylethyl)amide

: 164738-69-6
2-(Methoxymethyl)-3-phenyl-2-propenoic acid

: methyl (R)-3-[N-benzyl-N-((S)-1-phenylethyl)amino]-2-{[N-benzyl-N-((S)-phenylethyl)amino]methyl}-3-phenyl-propionate

: 950580-16-2
methyl 2-{(S)-[N-benzyl-N-((S)-1-phenylethyl)amino]phenylmethyl}acrylate

: methyl (R)-3-[N-benzyl-N-((S)-1-phenylethyl)amino]-2-{[N-benzyl-N-((S)-phenylethyl)amino]methyl}-3-phenyl-propionate

Guidance literature:: methanol; 2-(Methoxymethyl)-3-phenyl-2-propenoic acid; With thionyl chloride; at 20 ℃; for 15h;

lithium N-benzyl-N-((S)-1-phenylethyl)amide; In tetrahydrofuran; Petroleum ether; at -78 ℃; for 1h; Further stages.;
DOI:10.1016/j.tetasy.2007.06.010

Reference yield:

: C₂₅H₂₇NO₂

: 950580-16-2
methyl 2-{(S)-[N-benzyl-N-((S)-1-phenylethyl)amino]phenylmethyl}acrylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: LDA / tetrahydrofuran; petroleum ether / 1 h / -78 °C

1.2: ZnBr₂ / tetrahydrofuran; petroleum ether / 0.5 h / -78 °C

1.3: 56 percent / tetrahydrofuran; petroleum ether / 1 h / -78 °C

2.1: 85 percent / MsCl; (1,3-diazabicyclo[5.4.0]undecane / dioxane / 16 h / 60 °C

With methanesulfonyl chloride; lithium diisopropyl amide; In tetrahydrofuran; 1,4-dioxane; Petroleum ether;
DOI:10.1016/j.tetasy.2007.06.010