DODECYL PHOSPHOCHOLINE

Base Information

• Chemical Name: DODECYL PHOSPHOCHOLINE
• CAS No.: 29557-51-5
• Molecular Formula: C₁₇H₃₈NO₄P
• Molecular Weight: 351.467
• Hs Code.: 2923900090
• Mol file: 29557-51-5.mol

Synonyms:Choline,hydroxide, dodecyl hydrogen phosphate, inner salt (8CI); 2-(Trimethylammonio)ethyldodecyl phosphate; D 23170; Dodecylphosphocholine; FOS-Choline 12;n-Dodecylphosphocholine; n-Dodecylphosphorylcholine

Chemical Property of DODECYL PHOSPHOCHOLINE

Chemical Property:

• Melting Point: 224-226 °C
• PSA: 68.40000
• LogP: 5.18530
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Dodecylphosphocholine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: n-Dodecylphosphocholine (unlabelled) (CAS# 29557-51-5) is a useful research compound. DODECYL PHOSPHOCHOLINE can be used to produce large amounts of function membrane of the protein, hERG.

Technology Process of DODECYL PHOSPHOCHOLINE

There total 5 articles about DODECYL PHOSPHOCHOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-dodecyl alcohol (112-53-8) → Dodecylphosphocholine (29557-51-5)

Guidance literature:

Multi-step reaction with 2 steps

1: diisopropylamine / ethyl acetate / 2 h / 0 - 20 °C

2: 9.1 g / acetonitrile; ethyl acetate / 12 h / 70 °C

With diisopropylamine; In ethyl acetate; acetonitrile;

DOI:10.1246/bcsj.78.1558

Reference yield:

1-[(2-oxo-1,3,2-dioxaphospholan-2-yl)oxy]dodecane (96720-29-5) + trimethylamine (75-50-3) → Dodecylphosphocholine (29557-51-5)

Guidance literature:

In acetonitrile; at 75 ℃; for 30h; Yield given;

DOI:10.1016/S0040-4039(00)98424-7

Reference yield:

dodecyl dichlorophosphate (77638-27-8) → Dodecylphosphocholine (29557-51-5)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / diethyl ether / 12 h / Ambient temperature

2: acetonitrile / 30 h / 75 °C

With triethylamine; In diethyl ether; acetonitrile;

DOI:10.1016/S0040-4039(00)98424-7

upstream raw materials:

1-[(2-oxo-1,3,2-dioxaphospholan-2-yl)oxy]dodecane

trimethylamine

Phosphoric acid 2-bromo-ethyl ester dodecyl ester

1-dodecyl alcohol