S-t-butyl 12-triphenylmethyloxy-11-benzyloxy-3-oxododecanethioate

Base Information

• Chemical Name: S-t-butyl 12-triphenylmethyloxy-11-benzyloxy-3-oxododecanethioate
• CAS No.: 127895-73-2
• Molecular Formula: C₄₂H₅₀O₄S
• Molecular Weight: 650.923
• Mol file: 127895-73-2.mol

Synonyms:S-t-butyl 12-triphenylmethyloxy-11-benzyloxy-3-oxododecanethioate

Chemical Property of S-t-butyl 12-triphenylmethyloxy-11-benzyloxy-3-oxododecanethioate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of S-t-butyl 12-triphenylmethyloxy-11-benzyloxy-3-oxododecanethioate

There total 1 articles about S-t-butyl 12-triphenylmethyloxy-11-benzyloxy-3-oxododecanethioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methyleneoxetan-2-one (674-82-8,2130-41-8) + 2-methylpropan-2-thiol (75-66-1) + 8-triphenylmethyloxy-7-benzyloxyoctyl iodide (127895-63-0) → S-t-butyl 12-triphenylmethyloxy-11-benzyloxy-3-oxododecanethioate (127895-73-2)

Guidance literature:

With n-butyllithium; sodium hydride; Yield given. Multistep reaction; 1.) DME/hexane, -30 deg C, 1 h; 2.) DME, -35 deg C, 1 h then 28 deg C, 1 h;

DOI:10.1016/S0040-4020(01)89218-8

Reference yield: 59.0%

S-t-butyl 12-triphenylmethyloxy-11-benzyloxy-3-oxododecanethioate (127895-73-2) → S-t-butyl 12-hydroxy-11-benzyloxy-3-oxodecanethioate (127895-80-1)

Guidance literature:

With Amerlyst IR 15; In methanol; at 0 ℃; for 1h;

DOI:10.1016/S0040-4020(01)89218-8

upstream raw materials:

4-methyleneoxetan-2-one

2-methylpropan-2-thiol

8-triphenylmethyloxy-7-benzyloxyoctyl iodide

Downstream raw materials:

S-t-butyl 12-hydroxy-11-benzyloxy-3-oxodecanethioate