Glycidyl methyl ether

Base Information

• Chemical Name: Glycidyl methyl ether
• CAS No.: 930-37-0
• Deprecated CAS: 126872-18-2
• Molecular Formula: C4H8 O2
• Molecular Weight: 88.1063
• Hs Code.: 2910900090
• European Community (EC) Number: 213-216-7
• NSC Number: 86950
• UN Number: 1992
• UNII: 87MK2KA66T
• DSSTox Substance ID: DTXSID9025613
• Nikkaji Number: J60.714B
• Wikidata: Q27269834
• Mol file: 930-37-0.mol

Synonyms:Denacol EX-131;EX-131 methyl glycidyl ether

Chemical Property of Glycidyl methyl ether

Chemical Property:

• Refractive Index: 1.4080-1.4140
• Boiling Point: 116.5°Cat760mmHg
• Flash Point: 8.1°C
• PSA: 21.76000
• Density: 0.998g/cm³
• LogP: 0.03160
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Toluene (Slightly)
• XLogP3: -0.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 88.052429494
• Heavy Atom Count: 6
• Complexity: 44.8
• Transport DOT Label: Flammable Liquid Poison

Purity/Quality:

99% ^*data from raw suppliers

2-(Methoxymethyl)oxirane ^*data from reagent suppliers

Safty Information:

• Statements: 10
• Safety Statements: 16

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Plastics & Rubber -> Glycidyl Ethers
• Canonical SMILES: COCC1CO1
• Uses: 2-(Methoxymethyl)oxirane is used in the fixation of biological tissues or in collagen bioprosthetic fixation processes.

Technology Process of Glycidyl methyl ether

There total 14 articles about Glycidyl methyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methylallylether (627-40-7) → glycidyl methyl ether (930-37-0)

Guidance literature:

With tetrabutylphosphonium peroxotantalate; dihydrogen peroxide; In water; acetonitrile; at 0 ℃; for 5.5h; chemoselective reaction; Schlenk technique;

DOI:10.1002/chem.201605661

Reference yield: 88.0%

1-chloro-3-methoxypropan-2-ol (4151-97-7) → glycidyl methyl ether (930-37-0)

Guidance literature:

With sodium hydroxide; at 5 ℃;

DOI:10.1021/jo00156a018

Reference yield: 15.0%

diethyl 2-amino-6-[(hydroxycarbamoyl)-methyl]-azulene-1,3-dicarboxylate sodium (227945-00-8) → glycidyl methyl ether (930-37-0) + diethyl 2-amino-6-[(2-hydroxy-3-methoxy-propoxycarbamoyl)-methyl]-azulene-1,3-dicarboxylate

Guidance literature:

upstream raw materials:

2-chloro-3-methoxy-propan-1-ol

1-chloro-3-methoxypropan-2-ol

methylallylether

methanol

Downstream raw materials:

N-(2-hydroxy-3-methoxypropyl)piperazine

N,N'-bis(2-hydroxy-3-methoxypropyl)piperazine

4-methoxymethyl-1,3-dioxolan-2-one

propene

Refernces

• 1、 Ding, Bingjie,Hou, Zhenshan,Li, Difan,Ma, Wenbao,Yao, Yefeng,Zhang, Ran,Zheng, Anna,Zhou, Qingqing. "Olefin epoxidation with ionic liquid catalysts formed by supramolecular interactions". . . Retrieved 2020/12/29.
• 2、 -. "Preparation method of nifuratel related substance A". Paragraph 0025-0027; 0032-0034; 0039-0041; 0046-0048; 0053. . Retrieved 2021/05/05.