(R)-5-(2-(benzylamino)ethyl)-1-(6,8-difluorochroman-3-yl)-1H-imidazole-2(3H)-thione

Base Information

Chemical Name:(R)-5-(2-(benzylamino)ethyl)-1-(6,8-difluorochroman-3-yl)-1H-imidazole-2(3H)-thione
CAS No.:1080028-80-3
Molecular Formula:C₂₁H₂₁F₂N₃OS
Molecular Weight:401.48
Hs Code.:

Synonyms:(R)-5-(2-(benzylamino)ethyl)-1-(6,8-difluorochroman-3-yl)-1H-imidazole-2(3H)-thione

Suppliers and Price of (R)-5-(2-(benzylamino)ethyl)-1-(6,8-difluorochroman-3-yl)-1H-imidazole-2(3H)-thione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
Zamicastat
002
$ 1100.00

DC Chemicals
Zamicastat
001
$ 600.00

DC Chemicals
Zamicastat
003
$ 1900.00

ChemScene
Zamicastat 99.85%
100mg
$ 2100.00

ChemScene
Zamicastat 99.85%
50mg
$ 1350.00

ChemScene
Zamicastat 99.85%
10mg
$ 450.00

ChemScene
Zamicastat 99.85%
5mg
$ 250.00

Total 8 raw suppliers

Chemical Property of (R)-5-(2-(benzylamino)ethyl)-1-(6,8-difluorochroman-3-yl)-1H-imidazole-2(3H)-thione

Chemical Property:

Boiling Point:525.8±60.0 °C(Predicted)
Density:1.36±0.1 g/cm3(Predicted)

Purity/Quality:

99%, ^*data from raw suppliers

Zamicastat ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-5-(2-(benzylamino)ethyl)-1-(6,8-difluorochroman-3-yl)-1H-imidazole-2(3H)-thione

There total 7 articles about (R)-5-(2-(benzylamino)ethyl)-1-(6,8-difluorochroman-3-yl)-1H-imidazole-2(3H)-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1383828-47-4
(R)-5-(2-(benzylamino)ethyl)-1-(6,8-difluorochroman-3-yl)-1H-imidazole-2(3H)-thione hydrochloride

: 1080028-80-3
(R)-5-(2-(benzylamino)ethyl)-1-(6,8-difluorochroman-3-yl)-1H-imidazole-2(3H)-thione

Guidance literature:: With sodium hydroxide; In methanol; water; at 67 - 68 ℃; for 1.5h;

Reference yield: 76.0%

: 1417179-41-9
(R)-N-benzyl-2-(3-(6,8-difluorochroman-3-yl)-2-thioxo-2,3-dihydro-1H-imidazol-4-yl)acetamide

: 1080028-80-3
(R)-5-(2-(benzylamino)ethyl)-1-(6,8-difluorochroman-3-yl)-1H-imidazole-2(3H)-thione

Guidance literature:: With sodium tetrahydroborate; boron trifluoride diethyl etherate; In tetrahydrofuran; at 25 ℃; for 7h; Time; Concentration; Cooling with ice; Inert atmosphere;