oct-7-en-4-ynyloxymethyl-benzene

Base Information

• Chemical Name: oct-7-en-4-ynyloxymethyl-benzene
• CAS No.: 912365-49-2
• Molecular Formula: C₁₅H₁₈O
• Molecular Weight: 214.307
• Mol file: 912365-49-2.mol

Synonyms:oct-7-en-4-ynyloxymethyl-benzene

Chemical Property of oct-7-en-4-ynyloxymethyl-benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of oct-7-en-4-ynyloxymethyl-benzene

There total 3 articles about oct-7-en-4-ynyloxymethyl-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

5-benzyloxy-1-pentyne (57618-47-0) + allyl bromide (106-95-6) → oct-7-en-4-ynyloxymethyl-benzene (912365-49-2)

Guidance literature:

5-benzyloxy-1-pentyne; allyl bromide; With copper(l) iodide; potassium carbonate;

With tetra-(n-butyl)ammonium iodide; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

DOI:10.1016/j.tetlet.2006.07.044

Reference yield:

pent-1-yn-5-ol (5390-04-5) → oct-7-en-4-ynyloxymethyl-benzene (912365-49-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 94 percent / NaH / tetrahydrofuran / 5 h / 0 - 20 °C

2.1: CuI; K₂CO₃

2.2: 77 percent / TBAI / dimethylformamide / 12 h / 20 °C

With copper(l) iodide; sodium hydride; potassium carbonate; In tetrahydrofuran;

DOI:10.1016/j.tetlet.2006.07.044

Reference yield:

benzyl bromide (100-39-0) → oct-7-en-4-ynyloxymethyl-benzene (912365-49-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 94 percent / NaH / tetrahydrofuran / 5 h / 0 - 20 °C

2.1: CuI; K₂CO₃

2.2: 77 percent / TBAI / dimethylformamide / 12 h / 20 °C

With copper(l) iodide; sodium hydride; potassium carbonate; In tetrahydrofuran;

DOI:10.1016/j.tetlet.2006.07.044

upstream raw materials:

5-benzyloxy-1-pentyne

allyl bromide

pent-1-yn-5-ol

benzyl bromide

Downstream raw materials:

(R)-4-Benzyl-3-[(2R,3S,9S)-9-(tert-butyl-diphenyl-silanyloxy)-3-hydroxy-2-(4-methoxy-benzyloxy)-decanoyl]-oxazolidin-2-one

(R)-4-Benzyl-3-[(2R,3S,9S)-9-(tert-butyl-diphenyl-silanyloxy)-2,3-dihydroxy-decanoyl]-oxazolidin-2-one

(7-benzyloxy-1-methyl-hept-3-ynyloxy)-tert-butyl-diphenyl-silane

7-(tert-butyl-diphenyl-silanyloxy)-octanal