1,1'-<<(butane-1,4-diyl)dioxy>bis<(2-nitro-5-methoxy-1,4-phenylene)carbonyl>>bis

Base Information

• Chemical Name: 1,1'-<<(butane-1,4-diyl)dioxy>bis<(2-nitro-5-methoxy-1,4-phenylene)carbonyl>>bis
• CAS No.: 145325-50-4
• Molecular Formula: C₃₈H₅₄N₄O₁₀S₄
• Molecular Weight: 855.132
• Mol file: 145325-50-4.mol

Synonyms:1,1'-<<(butane-1,4-diyl)dioxy>bis<(2-nitro-5-methoxy-1,4-phenylene)carbonyl>>bis

Chemical Property of 1,1'-<<(butane-1,4-diyl)dioxy>bis<(2-nitro-5-methoxy-1,4-phenylene)carbonyl>>bis

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1'-<<(butane-1,4-diyl)dioxy>bis<(2-nitro-5-methoxy-1,4-phenylene)carbonyl>>bis

There total 7 articles about 1,1'-<<(butane-1,4-diyl)dioxy>bis<(2-nitro-5-methoxy-1,4-phenylene)carbonyl>>bis which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

(2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-pyrrole (105089-88-1) + 1',4'-bis(4-carboxy-2-methoxy-5-nitrophenoxy)butane (145325-47-9) → 1,1'-<<(butane-1,4-diyl)dioxy>bis<(2-nitro-5-methoxy-1,4-phenylene)carbonyl>>bis (145325-50-4)

Guidance literature:

With oxalyl dichloride; water; triethylamine; In tetrahydrofuran; for 4h;

DOI:10.1039/c39920001518

Reference yield:

C30H34N4O12 (322391-17-3) + ethanethiol (75-08-1) → 1,1'-<<(butane-1,4-diyl)dioxy>bis<(2-nitro-5-methoxy-1,4-phenylene)carbonyl>>bis (145325-50-4)

Guidance literature:

With chloro-trimethyl-silane; In dichloromethane; at 30 ℃; for 24h;

DOI:10.1016/0040-4039(95)00744-W

Reference yield:

1',4'-bis<2-methoxy-(4-methoxycarbonyl)phenoxy>butane (130107-97-0) → 1,1'-<<(butane-1,4-diyl)dioxy>bis<(2-nitro-5-methoxy-1,4-phenylene)carbonyl>>bis (145325-50-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 68 percent / SnCl₄, HNO₃ / CH₂Cl₂ / 0.25 h / -25 °C

2: 93 percent / NaOH / tetrahydrofuran; H₂O / 6 h / 40 °C

3: 1) oxalyl chloride, DMF, 2) Et₃N / 1) THF, 4 h, 2) THF, H₂O, 0 deg C -> room temperature; room temperature, 1.5 h

With sodium hydroxide; oxalyl dichloride; nitric acid; tin(IV) chloride; triethylamine; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane; water;

DOI:10.1021/jo951631s

upstream raw materials:

(2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-pyrrole

1',4'-bis(4-carboxy-2-methoxy-5-nitrophenoxy)butane

C₃₀H₃₄N₄O₁₂

ethanethiol

Downstream raw materials:

1,1'-<<(butane-1,4-diyl)dioxy>bis<(2-amino-5-methoxy-1,4-phenylene)carbonyl>>bis