6-Quinoxalinamine,N,3,5-trimethyl-(9CI)

Base Information

• Chemical Name: 6-Quinoxalinamine,N,3,5-trimethyl-(9CI)
• CAS No.: 156243-44-6
• Molecular Formula: C₁₁H₁₃N₃
• Molecular Weight: 187.244
• Mol file: 156243-44-6.mol

Synonyms:6-Quinoxalinamine,N,3,5-trimethyl-(9CI);N,3,5-TRIMETHYLQUINOXALIN-6-AMINE

Chemical Property of 6-Quinoxalinamine,N,3,5-trimethyl-(9CI)

Chemical Property:

• Vapor Pressure: 0.000109mmHg at 25°C
• Refractive Index: 1.6500 (estimate)
• Boiling Point: 336.8°C at 760 mmHg
• PKA: 3.23±0.48(Predicted)
• Flash Point: 157.5°C
• PSA: 37.81000
• Density: 1.155g/cm³
• LogP: 2.36130

Purity/Quality:

99% ^*data from raw suppliers

6-QUINOXALINAMINE,N,3,5-TRIMETHYL- 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Quinoxalinamine,N,3,5-trimethyl-(9CI)

There total 4 articles about 6-Quinoxalinamine,N,3,5-trimethyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,N1-Dimethyl-4-nitro-benzene-1,3-diamine (156243-43-5) + 2-oxopropanal (78-98-8) → N,3,8-trimethylquinoxalin-6-amine (103139-97-5) + 2,8-dimethyl-7-methylaminoquinoxaline (156243-44-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; Yield given. Multistep reaction;

DOI:10.1248/cpb.42.408

Reference yield:

3-fluoro-2-methylaniline (443-86-7) → 2,8-dimethyl-7-methylaminoquinoxaline (156243-44-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 2.) HNO₃

2: 68 percent / 100 °C

3: 95 percent / HCl

4: 1.) H₂ / 1.) Pd/C

With hydrogenchloride; hydrogen; nitric acid; palladium on activated charcoal;

DOI:10.1248/cpb.42.408

Reference yield:

N-(3-Fluoro-2-methyl-6-nitro-phenyl)-acetamide (156243-41-3) → 2,8-dimethyl-7-methylaminoquinoxaline (156243-44-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 68 percent / 100 °C

2: 95 percent / HCl

3: 1.) H₂ / 1.) Pd/C

With hydrogenchloride; hydrogen; palladium on activated charcoal;

DOI:10.1248/cpb.42.408

upstream raw materials:

2,N¹-Dimethyl-4-nitro-benzene-1,3-diamine

2-oxopropanal

3-fluoro-2-methylaniline

N-(3-Fluoro-2-methyl-6-nitro-phenyl)-acetamide

Downstream raw materials:

2-amino-1,7,9-trimethylimidazo<4,5-g>quinoxaline

1,2,7,9-tetramethylimidazo<4,5-g>quinoxaline

Refernces