(2E)-N-(5,5,5-trifluoro-4-hydroxy-2-pentenyl)-N-(2-propynyl)tosylamide

Base Information

Chemical Name:(2E)-N-(5,5,5-trifluoro-4-hydroxy-2-pentenyl)-N-(2-propynyl)tosylamide
CAS No.:384836-09-3
Molecular Formula:C₁₅H₁₆F₃NO₃S
Molecular Weight:347.358
Hs Code.:

Synonyms:(2E)-N-(5,5,5-trifluoro-4-hydroxy-2-pentenyl)-N-(2-propynyl)tosylamide

Suppliers and Price of (2E)-N-(5,5,5-trifluoro-4-hydroxy-2-pentenyl)-N-(2-propynyl)tosylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (2E)-N-(5,5,5-trifluoro-4-hydroxy-2-pentenyl)-N-(2-propynyl)tosylamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (2E)-N-(5,5,5-trifluoro-4-hydroxy-2-pentenyl)-N-(2-propynyl)tosylamide

There total 3 articles about (2E)-N-(5,5,5-trifluoro-4-hydroxy-2-pentenyl)-N-(2-propynyl)tosylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 384836-87-7
(2E)-N-(3-formyl-2-propenyl)-N-(2-propynyl)tosylamide

: 384836-09-3
(2E)-N-(5,5,5-trifluoro-4-hydroxy-2-pentenyl)-N-(2-propynyl)tosylamide

Guidance literature:: With cesium fluoride; In 1,2-dimethoxyethane; at 20 ℃; for 0.5h;
DOI:10.1016/S0022-1139(01)00436-5

Reference yield:

: 463963-14-6
N-[(2E)-4-hydroxybut-2-en-1-yl]-4-methyl-N-prop-2-yn-1-ylbenzenesulfonamide

: 384836-09-3
(2E)-N-(5,5,5-trifluoro-4-hydroxy-2-pentenyl)-N-(2-propynyl)tosylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / Dess-Martin periodinane / CH₂Cl₂ / 0.5 h / 20 °C

2: 39 percent / CsF / 1,2-dimethoxy-ethane / 0.5 h / 20 °C

With Dess-Martin periodane; cesium fluoride; In 1,2-dimethoxyethane; dichloromethane;
DOI:10.1016/S0022-1139(01)00436-5

Reference yield:

: 384836-85-5
ethyl (E)-4-(N-(prop-2-ynyl)-4-methylphenylsulfonamido)but-2-enoate

: 384836-09-3
(2E)-N-(5,5,5-trifluoro-4-hydroxy-2-pentenyl)-N-(2-propynyl)tosylamide

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / DIBAH / toluene / 0.5 h / -78 °C

2: 77 percent / Dess-Martin periodinane / CH₂Cl₂ / 0.5 h / 20 °C

3: 39 percent / CsF / 1,2-dimethoxy-ethane / 0.5 h / 20 °C

With diisobutylaluminium hydride; Dess-Martin periodane; cesium fluoride; In 1,2-dimethoxyethane; dichloromethane; toluene;
DOI:10.1016/S0022-1139(01)00436-5