4-(Chloropropyl)-1-(2-quinolyl)piperazine

Base Information

Chemical Name:4-(Chloropropyl)-1-(2-quinolyl)piperazine
CAS No.:131060-08-7
Molecular Formula:C₁₆H₂₀ClN₃
Molecular Weight:289.808
Hs Code.:
DSSTox Substance ID:DTXSID10156860
Nikkaji Number:J399.539I
Wikidata:Q83024975
Mol file:131060-08-7.mol

Synonyms:4-(chloropropyl)-1-(2-quinolyl)piperazine;4-CPQP

Suppliers and Price of 4-(Chloropropyl)-1-(2-quinolyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-(Chloropropyl)-1-(2-quinolyl)piperazine

Chemical Property:

Vapor Pressure:1.51E-07mmHg at 25°C
Boiling Point:453.9°Cat760mmHg
Flash Point:228.3°C
PSA：19.37000
Density:1.18g/cm³
LogP:2.98860
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:289.1345753
Heavy Atom Count:20
Complexity:291

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCCCl)C2=NC3=CC=CC=C3C=C2

Technology Process of 4-(Chloropropyl)-1-(2-quinolyl)piperazine

There total 2 articles about 4-(Chloropropyl)-1-(2-quinolyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 4774-24-7
2-(piperazin-1-yl)quinoline

: 109-70-6
1.3-chlorobromopropane

: 131060-08-7
4-(chloropropyl)-1-(2-quinolyl)piperazine

Guidance literature:: With sodium hydroxide; In water; acetone; at 20 ℃;

Reference yield:

: 612-62-4
2-Chloroquinoline

: 131060-08-7
4-(chloropropyl)-1-(2-quinolyl)piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / KOH / toluene / 4 h / Heating

2: 84 percent / KOH / toluene / 4 h / Heating

With potassium hydroxide; In toluene;
DOI:10.1002/jps.2600810120

Reference yield:

: 131060-08-7
4-(chloropropyl)-1-(2-quinolyl)piperazine

: 6969-71-7
[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

: 139477-46-6
2-<3-<4-<2-(quinolyl)>-1-piperazinyl>propyl>-1,2,4-triazolo<4,3-a>pyridin-3(2H)-one

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1.) xylene, reflux, 1 h, 2.) xylene, 150 deg C, 20 h;
DOI:10.1002/jps.2600810120