N-benzyl-3-phenyl-N-(3-phenylprop-2-yn-1-yl)prop-2-yn-1-amine

Base Information

• Chemical Name: N-benzyl-3-phenyl-N-(3-phenylprop-2-yn-1-yl)prop-2-yn-1-amine
• CAS No.: 345983-67-7
• Molecular Formula: C₂₅H₂₁N
• Molecular Weight: 335.448
• Mol file: 345983-67-7.mol

Synonyms:N-benzyl-3-phenyl-N-(3-phenylprop-2-yn-1-yl)prop-2-yn-1-amine

Chemical Property of N-benzyl-3-phenyl-N-(3-phenylprop-2-yn-1-yl)prop-2-yn-1-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-benzyl-3-phenyl-N-(3-phenylprop-2-yn-1-yl)prop-2-yn-1-amine

There total 4 articles about N-benzyl-3-phenyl-N-(3-phenylprop-2-yn-1-yl)prop-2-yn-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 1-Phenyl-2-(trimethylsilyl)acetylene (2170-06-1) + benzylamine (100-46-9) → N-benzyl-3-phenyl-N-(3-phenylprop-2-yn-1-yl)prop-2-yn-1-amine (345983-67-7)

Guidance literature:

With copper(II) bis(trifluoromethanesulfonate); copper(l) chloride; In acetonitrile; at 100 ℃; for 24h;

DOI:10.1055/S-2008-1077790

Reference yield: 73.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + benzylamine (100-46-9) + phenylpropyolic acid (637-44-5) → N-benzyl-3-phenyl-N-(3-phenylprop-2-yn-1-yl)prop-2-yn-1-amine (345983-67-7)

Guidance literature:

With Dihydroxy-isobutyl-boran; In 1,2-dichloro-ethane; at 45 ℃; for 10h; chemoselective reaction; Sealed tube;

DOI:10.1021/jo502349a

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + phenylacetylene (536-74-3) + benzylamine (100-46-9) → N-benzyl-3-phenyl-N-(3-phenylprop-2-yn-1-yl)prop-2-yn-1-amine (345983-67-7)

Guidance literature:

With copper(l) iodide; In aq. phosphate buffer; dimethyl sulfoxide; at 20 ℃; for 48h; pH=7.8;

DOI:10.1002/chem.201605938

upstream raw materials:

formaldehyd

1-Phenyl-2-(trimethylsilyl)acetylene

benzylamine

phenylpropyolic acid