Diethyl 2,3-diethoxysuccinate

Base Information

• Chemical Name: Diethyl 2,3-diethoxysuccinate
• CAS No.: 7153-16-4
• Molecular Formula: C12H22O6
• Molecular Weight: 262.2995
• NSC Number: 60924
• DSSTox Substance ID: DTXSID30992020
• Mol file: 7153-16-4.mol

Synonyms:7153-16-4;diethyl 2,3-diethoxysuccinate;diethyl 2,3-diethoxybutanedioate;Succinic acid, 2,3-diethoxy-, diethyl ester;NSC60924;Succinic acid, alpha,beta-diethoxy-, diethyl ester;NCIOpen2_002611;DTXSID30992020;KWALRSPAGVOALG-UHFFFAOYSA-N;NSC 60924;NSC-60924;AKOS024336559;2,3-Diethoxybutandioic acid diethyl ester

Chemical Property of Diethyl 2,3-diethoxysuccinate

Chemical Property:

• Vapor Pressure: 0.000303mmHg at 25°C
• Boiling Point: 321.2°C at 760 mmHg
• Flash Point: 136.6°C
• Density: 1.061g/cm³
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 11
• Exact Mass: 262.14163842
• Heavy Atom Count: 18
• Complexity: 227

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(C(C(=O)OCC)OCC)C(=O)OCC

Technology Process of Diethyl 2,3-diethoxysuccinate

There total 6 articles about Diethyl 2,3-diethoxysuccinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-chloro-2-ethoxyacetate (34006-60-5) → di-O-ethyl-DL-tartaric acid diethyl ester (7153-16-4,36685-10-6,36685-11-7,77398-14-2)

Guidance literature:

With copper; at 80 ℃;

Reference yield:

ethyl 2-bromo-2-ethoxy-acetate (57941-45-4) → di-O-ethyl-DL-tartaric acid diethyl ester (7153-16-4,36685-10-6,36685-11-7,77398-14-2)

Guidance literature:

With copper; at 80 ℃;

Reference yield:

Ethyl diethoxyacetate (6065-82-3) → di-O-ethyl-DL-tartaric acid diethyl ester (7153-16-4,36685-10-6,36685-11-7,77398-14-2)

Guidance literature:

Multi-step reaction with 2 steps

1: PCl₅ / 80 - 140 °C

2: copper / 80 °C

With phosphorus pentachloride; copper;

upstream raw materials:

ethyl 2-chloro-2-ethoxyacetate

ethyl 2-bromo-2-ethoxy-acetate

(+/-)-diethyl tartrate

ethyl iodide