N-(2-Hydroxyethyl)nicotinamide

Base Information

Chemical Name:N-(2-Hydroxyethyl)nicotinamide
CAS No.:6265-73-2
Molecular Formula:C8H10N2O2
Molecular Weight:166.18
Hs Code.:2933399090
European Community (EC) Number:811-328-6
NSC Number:33142
UNII:MHH3UT8GRP
DSSTox Substance ID:DTXSID30211708
Nikkaji Number:J86.485D
Wikidata:Q83086682
ChEMBL ID:CHEMBL3264036
Mol file:6265-73-2.mol

Synonyms:N-(2-hydroxyethyl)nicotinamide;SG 86;SG-86

Suppliers and Price of N-(2-Hydroxyethyl)nicotinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(2-Hydroxyethyl)nicotinamide
250mg
$ 105.00

Medical Isotopes, Inc.
N-(2-Hydroxyethyl)nitotinamide
1 g
$ 625.00

Matrix Scientific
N-(2-Hydroxyethyl)nitotinamide 95+%
5g
$ 1607.00

Matrix Scientific
N-(2-Hydroxyethyl)nitotinamide 95+%
250mg
$ 278.00

Matrix Scientific
N-(2-Hydroxyethyl)nitotinamide 95+%
1g
$ 599.00

Crysdot
N-(2-Hydroxyethyl)nicotinamide 95+%
10g
$ 412.00

Crysdot
N-(2-Hydroxyethyl)nicotinamide 95+%
5g
$ 257.00

Crysdot
N-(2-Hydroxyethyl)nicotinamide 95+%
25g
$ 774.00

Chemenu
N-(2-Hydroxyethyl)nicotinamide 95%
25g
$ 731.00

Chemenu
N-(2-Hydroxyethyl)nicotinamide 95%
5g
$ 242.00

Total 50 raw suppliers

Chemical Property of N-(2-Hydroxyethyl)nicotinamide

Chemical Property:

Vapor Pressure:1.28E-08mmHg at 25°C
Melting Point:92 °C
Refractive Index:1.557
Boiling Point:442.8 °C at 760 mmHg
PKA:12.94±0.46(Predicted)
Flash Point:221.6 °C
PSA：62.22000
Density:1.212g/cm³
LogP:0.19460
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Solubility.:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
XLogP3:-0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:166.074227566
Heavy Atom Count:12
Complexity:150

Purity/Quality:

99%, ^*data from raw suppliers

N-(2-Hydroxyethyl)nicotinamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CN=C1)C(=O)NCCO
Uses N-(2-Hydroxyethyl)nitotinamide is an intermediate used to prepare oxadiazole oxide derivatives as vasodilators. It is also a derivative of Nicorandil (N398500) which is an antiaginal.

Technology Process of N-(2-Hydroxyethyl)nicotinamide

There total 1 articles about N-(2-Hydroxyethyl)nicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 88598-33-8
2-aminoethyl nicotinate nitrate

: 59-67-6
nicotinic acid

: 6265-73-2
N-(2-hydroxyethyl)nicotinamide

Guidance literature:: at 60 ℃; for 7h; Rate constant; Mechanism; Thermodynamic data; variation of pH; Δ Eexcit;
DOI:10.1248/cpb.32.1063

Reference yield: 87.0%

: 6265-73-2
N-(2-hydroxyethyl)nicotinamide

: 76016-68-7
3-nitro-4-phenylfurazane

: N-[2-(4-phenyl-furazan-3-yloxy)-ethyl]-nicotinamide

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; at 25 ℃; for 4h;
DOI:10.1016/S0968-0896(00)00098-5

Reference yield: 86.0%

: 6265-73-2
N-(2-hydroxyethyl)nicotinamide

: 65141-46-0
N-(2-nitroxyethyl)nicotinamide

Guidance literature:: With nitric acid; urea; europium(III) trifluoromethanesulfonate; at 70 ℃; for 6h; Schlenk technique;
DOI:10.1039/d0ob01519a