Technology Process of 2,4,6-trihydroxy-5-methoxyacetophenone
There total 8 articles about 2,4,6-trihydroxy-5-methoxyacetophenone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C / Cooling with ice
2: 3-chloro-benzenecarboperoxoic acid / dichloromethane; water / 20 °C
3: potassium carbonate / acetone / 56 °C / Inert atmosphere
4: hydrogenchloride / water; methanol / 20 °C
5: boron trifluoride diethyl etherate / 20 °C / Cooling with ice; Inert atmosphere
With
hydrogenchloride; boron trifluoride diethyl etherate; potassium carbonate; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid;
In
methanol; dichloromethane; water; acetone;
2: |Baeyer-Villiger Ketone Oxidation / 5: |Friedel-Crafts Acylation;
DOI:10.1021/acs.jnatprod.5b00324
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrogenchloride / water; methanol / 20 °C
2: boron trifluoride diethyl etherate / 20 °C / Cooling with ice; Inert atmosphere
With
hydrogenchloride; boron trifluoride diethyl etherate;
In
methanol; water;
2: |Friedel-Crafts Acylation;
DOI:10.1021/acs.jnatprod.5b00324
