5-(4-Chloro-3-nitrophenyl)-1,3,4-thiadiazol-2-amine

Base Information

Chemical Name:5-(4-Chloro-3-nitrophenyl)-1,3,4-thiadiazol-2-amine
CAS No.:109702-87-6
Molecular Formula:C₈H₅ClN₄O₂S
Molecular Weight:256.672
Hs Code.:
DSSTox Substance ID:DTXSID501327995
ChEMBL ID:CHEMBL1543693

Synonyms:5-(4-chloro-3-nitrophenyl)-1,3,4-thiadiazol-2-amine;109702-87-6;MLS000710329;CHEMBL1543693;DTXSID501327995;HMS2699G11;STK392797;AKOS000413978;SMR000279074;CS-0366929;AG-690/11425018;2-amino-5-{4-chloro-3-nitrophenyl}-1,3,4-thiadiazole;5-(4-Chloro-3-nitrophenyl)-1,3,4-thiadiazol-2-ylamine

Suppliers and Price of 5-(4-Chloro-3-nitrophenyl)-1,3,4-thiadiazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 5-(4-Chloro-3-nitrophenyl)-1,3,4-thiadiazol-2-amine

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:255.9821743
Heavy Atom Count:16
Complexity:277

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C=C1C2=NN=C(S2)N)[N+](=O)[O-])Cl

Technology Process of 5-(4-Chloro-3-nitrophenyl)-1,3,4-thiadiazol-2-amine

There total 4 articles about 5-(4-Chloro-3-nitrophenyl)-1,3,4-thiadiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 28004-62-8
2-amino-5-(4-chlorophenyl)-1,3,4-thiadiazole

: 109702-87-6
2-amino-5-(4-chloro-3-nitrophenyl)-1,3,4-thiadiazole

Guidance literature:: With sulfuric acid; nitric acid; at 0 ℃; for 1h;

Reference yield: 35.0%

: C₈H₇ClN₄O₃S

: 109702-87-6
2-amino-5-(4-chloro-3-nitrophenyl)-1,3,4-thiadiazole

Guidance literature:: With sulfuric acid;
DOI:10.2174/1570180814666170512122832

Reference yield:

: 96-99-1
4-chloro-3-nitrobenzoate

: 109702-87-6
2-amino-5-(4-chloro-3-nitrophenyl)-1,3,4-thiadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride; N,N-dimethyl-formamide / toluene

2: sulfuric acid

With thionyl chloride; sulfuric acid; N,N-dimethyl-formamide; In toluene;
DOI:10.2174/1570180814666170512122832